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View Structure Prediction Details

Protein: SYKM_ARATH
Organism: Arabidopsis thaliana
Length: 602 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SYKM_ARATH.

Description E-value Query
Range
Subject
Range
SYK_IDILO - Lysine--tRNA ligase OS=Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) GN=lysS PE=3 ...
SYK_IDILO - Lysyl-tRNA synthetase OS=Idiomarina loihiensis GN=lysS PE=3 SV=1
534.0 [0..70] [601..1]

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Predicted Domain #1
Region A:
Residues: [1-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEALKVWSLT ATPLKQLLRL SSSSTRLATT IYGRRSYHLS PALRCASAAS SSSSSATTAE  60
   61 TSKPSGRNRR SASSSNSTSD REAIRSIRLK KVEELRGQGL EPYAYKWEKS HSANQLQEIY 120
  121 KHLANGEESD NEIDCVSIAG RVVARRAFGK LAFLTLRDDS GTIQLYCEKE RLSDDQFEQL 180
  181 KQFIDIGDIL GASGSMKRTE KGELSICVNS FSILTKSLLP LPDKYHGLTD IDKRYRQRYV 240
  241 DMIANPEVAD VFRRRAKIVS EIRKTVESFG YLEVETPVLQ GAAGGAEARP FVTFHNSLGR 300
  301 DLYLRIATEL HLKRMLVGGF EKVYEIGRIF RNEGISTRHN PEFTTIEMYE AYSDYHSMMD 360
  361 MAELIVTQCS MAVNGKLTID YQGTEICLER PWRRETMHNL VKEITGINFS ELGEDLGNAK 420
  421 DTVLLALQDV LEPKDKSGIR ACSSLGHLLN EIFEVVVEPK LVQPTFVLDY PIEISPLAKP 480
  481 HRGNAGLTER FELFICGREM ANAFSELTDP VDQRTRLEEQ VRQHNAKRAE AVRESPEPNA 540
  541 KKDDDDDESY EVTLDEDFLT ALEYGMPPAS GMGLGIDRLV MLLTNSASIR DVIAFPVLKL 600
  601 QQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 150.0
Match: 1e1oA
Description: Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine-tRNA ligase activity 5.79033103181143 bayes_pls_golite062009
aspartate-tRNA ligase activity 4.71689802574628 bayes_pls_golite062009
nucleic acid binding 3.89165617439497 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.53864660125764 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.53864660125764 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 3.52777284894652 bayes_pls_golite062009
DNA binding 3.38561002225202 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
binding 2.83465364476231 bayes_pls_golite062009
ligase activity 2.56279938346489 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
structural constituent of ribosome 2.43759174701552 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
structural molecule activity 2.08258913217268 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
transcription regulator activity 1.69669059514663 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
structure-specific DNA binding 1.28199205469179 bayes_pls_golite062009
single-stranded DNA binding 0.97496043954059 bayes_pls_golite062009
translation initiation factor activity 0.96756670903925 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
transcription factor activity 0.859071050218437 bayes_pls_golite062009
sequence-specific DNA binding 0.77755643935497 bayes_pls_golite062009
ribonuclease activity 0.702449673647117 bayes_pls_golite062009
RNA binding 0.18502033889261 bayes_pls_golite062009
protein binding 0.152645195799531 bayes_pls_golite062009
nuclease activity 0.111225677144242 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle