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Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: lysine-tRNA ligase activity
Acc: GO:0004824
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
Synonyms:
  • lysyl-tRNA synthetase activity
  • lysine-tRNA synthetase activity
  • lysyl-transfer RNA synthetase activity
  • lysine translase activity
  • lysyl-transfer ribonucleate synthetase activity
  • L-lysine-transfer RNA ligase activity
  • L-lysine:tRNALys ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 37 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004824 - lysine-tRNA ligase activity (interactive image map)

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