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View Structure Prediction Details

Protein: CAMK2_ARATH
Organism: Arabidopsis thaliana
Length: 599 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAMK2_ARATH.

Description E-value Query
Range
Subject
Range
gi|5020368 - gi|5020368|gb|AAD38059.1|AF153352_1 CDPK-related kinase 2 [Arabidopsis thaliana]
486.0 [0..6] [599..1]

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Predicted Domain #1
Region A:
Residues: [1-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGCTSKPSS SVKPNPYAPK DAVLQNDDST PAHPGKSPVR SSPAVKASPF FPFYTPSPAR  60
   61 HRRNKSRDGG GGESKSVTST PLRQLARAFH PPSPARHIRD VLRRRKEKKE AALPAARQQK 120
  121 EEEEREEVGL DKRFGFSKEL QSRIELGEEI GRGHFGYTCS AKFKKGELKD QEVAVKVIPK 180
  181 SKMTSAISIE DVRREVKILR ALSGHQNLVQ FYDAFEDNAN VYIVMELCGG GELLDRILAR 240
  241 GGKYSEDDAK AVLIQILNVV AFCHLQGVVH RDLKPENFLY TSKEENSMLK VIDFGLSDFV 300
  301 RPDERLNDIV GSAYYVAPEV LHRSYTTEAD VWSIGVIAYI LLCGSRPFWA RTESGIFRAV 360
  361 LKADPSFDEP PWPSLSFEAK DFVKRLLYKD PRKRMTASQA LMHPWIAGYK KIDIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.0
Match: 1opkA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 5.4586557943719 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.04467222534257 bayes_pls_golite062009
kinase activity 4.85903980916957 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.63692708178478 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 4.31938467136214 bayes_pls_golite062009
transferase activity 3.26787750561728 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
tubulin binding 2.18641675163967 bayes_pls_golite062009
cytoskeletal protein binding 2.12615078788254 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
microtubule binding 1.88110801192607 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
molecular adaptor activity 1.33740973673697 bayes_pls_golite062009
actin binding 1.33479685165255 bayes_pls_golite062009
gamma-tubulin binding 1.28511591054866 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
SH3/SH2 adaptor activity 1.2323381312171 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transcription regulator activity 1.10597058961079 bayes_pls_golite062009
nucleic acid binding 1.06086848160606 bayes_pls_golite062009
DNA binding 0.956433441855102 bayes_pls_golite062009
protein binding, bridging 0.83823250804321 bayes_pls_golite062009
transcription factor activity 0.790106588313006 bayes_pls_golite062009
structural constituent of cytoskeleton 0.612883428421652 bayes_pls_golite062009
transporter activity 0.553953601841147 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
transmembrane transporter activity 0.37676337669549 bayes_pls_golite062009
protein complex binding 0.343240719858581 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.2403700250846 bayes_pls_golite062009
MAP kinase activity 0.08504542461349 bayes_pls_golite062009
substrate-specific transporter activity 0.0611721261859464 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [416-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDILIFKQIK AYLRSSSLRK AALMALSKTL TTDELLYLKA QFAHLAPNKN GLITLDSIRL  60
   61 ALATNATEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.1
Match: 2aaoA
Description: Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [485-599]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESRIPDFL ALLNGLQYKG MDFEEFCAAS ISVHQHESLD CWEQSIRHAY ELFEMNGNRV  60
   61 IVIEELASEL GVGSSIPVHT ILNDWIRHTD GKLSFLGFVK LLHGVSTRQS LAKTR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1auiB
Description: Calcineurin regulatory subunit (B-chain)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.49668552859347 bayes_pls_golite062009
motor activity 3.25814691068414 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
tubulin binding 2.51210014078446 bayes_pls_golite062009
actin binding 2.38676888633305 bayes_pls_golite062009
microtubule binding 2.17136406283012 bayes_pls_golite062009
transcription regulator activity 1.77004149096367 bayes_pls_golite062009
nucleic acid binding 1.43263098461462 bayes_pls_golite062009
calcium ion binding 1.40919295397643 bayes_pls_golite062009
ion binding 1.36376383271837 bayes_pls_golite062009
metal ion binding 1.34827363853601 bayes_pls_golite062009
cation binding 1.34827363853601 bayes_pls_golite062009
DNA binding 1.34235138376625 bayes_pls_golite062009
protein binding 1.16246005294206 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.05536109719637 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.02622810676526 bayes_pls_golite062009
kinase activity 1.01041521285233 bayes_pls_golite062009
structural constituent of muscle 0.99845401805886 bayes_pls_golite062009
actin filament binding 0.836375875773328 bayes_pls_golite062009
structural molecule activity 0.800850121197479 bayes_pls_golite062009
G-protein beta/gamma-subunit binding 0.77824189826064 bayes_pls_golite062009
transporter activity 0.594904129738596 bayes_pls_golite062009
transmembrane transporter activity 0.346694954512987 bayes_pls_golite062009
transferase activity 0.297929823471296 bayes_pls_golite062009
myosin binding 0.125186564742711 bayes_pls_golite062009
structural constituent of cytoskeleton 0.116648335890738 bayes_pls_golite062009
microfilament motor activity 0.0834423172982799 bayes_pls_golite062009
substrate-specific transporter activity 0.0489908313324834 bayes_pls_golite062009

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