| Protein: | MCM5_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 727 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM5_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
539.0 | [0..1] | [726..1] |
|
Region A: Residues: [1-142] |
1 11 21 31 41 51
| | | | | |
1 MSGWDEGAVY YSDQPQFPEA GDAATISPHA VLTKFKEFIR NFEIEQNCFP YREALLDNPK 60
61 RLVVHLEDLL SFDSDLPSLI RSAPADYLPV FEKAAGEVLT GLKMREANEG GVMEEPLTRD 120
121 VQILLTSRED PVSMRLLGAQ YI
|
| Detection Method: |  |
| Confidence: | 44.522879 |
| Match: | 1ltlA |
| Description: | DNA replication initiator (cdc21/cdc54) N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [143-566] |
1 11 21 31 41 51
| | | | | |
1 SKLVKISGIS IAASRVKAKA TYVFLVCKNC KKTREVPCRP GLGGAIVPRS CDNIPQPGEE 60
61 PCPLDPWMVV PDRSQYVDQQ TLKLQENPED VPTGELPRNM LLSVDRHLVQ TIVPGTRLTV 120
121 MGIYSIFQAS SSSNSHKGAV AIRQPYIRVV GLEDTNEASS RGPANFTPDE EEEFKKFADS 180
181 QDVYKNICTK IAPSIFGHED VKRAAACLLF GGSRKSLPDG VKLRGDINVL LLGDPSTAKS 240
241 QFLKFVEKTA PIAVYTSGKG SSAAGLTASV IRDSSTREFY LEGGAMVLAD GGVVCIDEFD 300
301 KMRPEDRVAI HEAMEQQTIS IAKAGITTVL NSRTSVLAAA NPPSGRYDDL KTAQDNIDLQ 360
361 TTILSRFDLI FIVKDIRKYS QDKEIASHII RVHASANKFS DENTDSKEDN WLKRYIQYCR 420
421 ARCH
|
| Detection Method: | |
| Confidence: | 16.221849 |
| Match: | 1ksfX |
| Description: | N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| telomeric DNA binding | 2.0142766759353 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.782430219754236 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.700780808446722 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.6071273686445 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.569910969126728 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.568840867400671 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.568779924702229 | bayes_pls_golite062009 |
| nucleotide binding | 0.564275755355315 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.26252931460003 | bayes_pls_golite062009 |
| ATP binding | 0.1860481660648 | bayes_pls_golite062009 |
| exodeoxyribonuclease V activity | 0.185603938981231 | bayes_pls_golite062009 |
| RNA helicase activity | 0.18426050934025 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.152859582615242 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.14606996093053 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.138615225841109 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.13050483816765 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [567-657] |
1 11 21 31 41 51
| | | | | |
1 PRLSKDAAEN LQRKYVTIRM DMKRRAHETG EAAPIPITVR QLEAIVRLSE SLAKMRLSHE 60
61 ATPDDVDKAF KLFDTSTMDA ARSGINQQIN I
|
| Detection Method: | |
| Confidence: | 14.0 |
| Match: | 1ixsB |
| Description: | Holliday junction helicase RuvB |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [658-727] |
1 11 21 31 41 51
| | | | | |
1 TGEMANEIKQ AETQIKRRMG IGARLSERRL IEDLARMGMN DSMVRRALLI MHQRGEVEYQ 60
61 RERRSIVRKA
|
| Detection Method: | |
| Confidence: | 50.0 |
| Match: | 1ojlA |
| Description: | Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding |
Matching Structure (courtesy of the PDB): |
|
