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View Structure Prediction Details

Protein: gi|12324934, gi|...
Organism: Arabidopsis thaliana
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12324934, gi|....

Description E-value Query
Range
Subject
Range
gi|115483276, gi... - gi|37536642|ref|NP_922623.1| putative UDP-N-acetylmuramoylananyl-D-glutamate-2,6 -diaminopimelate li...
580.0 [0..45] [767..38]

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Predicted Domain #1
Region A:
Residues: [1-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFTFLSPHP VFLSLTGTTS SFSYKPVLLP FSRNSRTLTV AAGPARRNSY PNPADDDPPE  60
   61 APEDSMHGVS KFQQIQRQAA RARKLEEEDF EKNRNTYLSA IADVEDAAET GRDDEESGGD 120
  121 LFSDIDRAIS MKRSEFVKQG LLKPNPPKTA SLKKIGEEGN EEEGDVTDDV DELDEEEVVD 180
  181 LDEIDKLTGL TEISDEEDWV DEEGNTRINK KKEFGSDHQF EFDLDDFGES KARIVEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [238-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFKMCLAELL DESKVVPISV YGDLDVEITG IQHDSRGVSA GDLFVCCLGS ENFLSEADKR  60
   61 GAVAVVASKE IDIEDTLGCR ALVIVEDTNA VLAALASSFY RHPSKNMSVI GVTGTDGKTT 120
  121 TTYLIKSLYE AMGVRTGMFS TVSCYIHGDN KLDTPNATMN PDAVLVQSLM AKMLHNGTES 180
  181 LVMEASPQEL ALGKCDEVDF DIAVFTNLTR ENTDFRGTDE EYRDAEAKLF SRMVDPERHR 240
  241 KVVNIDDPNA AFFVQQGNPN VPVVTFAMEN TKADVHPLKF ELSLFETQVL VNTPQGILEI 300
  301 SSGLLGRHNI YNILAAVAVG IAVGAPLEDI VRGVEEVDAV PGRCELIDEE QAFGVIVDHA 360
  361 NTPDGLSRLL DSIRELKPRR IITVIGCEGE NERGKRPLMT KIATEKSDVT MLTSDNPRNE 420
  421 DPLDILDDML SGIGWTMQEY LKHGEHDYYP PLANGHRLFL HDIRRVAVRC AVAMGEEGDM 480
  481 VVVAGKGHEA YQLEGEKKEF YDDREECREA LQYVDELHQA GIDTSEFPWR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.0
Match: 1e8cA
Description: UDP-N-acetylmuramyl tripeptide synthetase MurE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acid-amino acid ligase activity 4.86493054281191 bayes_pls_golite062009
catalytic activity 3.03081854683329 bayes_pls_golite062009
UDP-N-acetylmuramate-L-alanine ligase activity 2.62956763198067 bayes_pls_golite062009
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity 2.38541436302257 bayes_pls_golite062009
ligase activity 2.2556848409907 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.19206014001612 bayes_pls_golite062009
UDP-N-acetylmuramoylalanine-D-glutamate ligase activity 1.471039191151 bayes_pls_golite062009
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity 1.15437935952018 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle