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View Structure Prediction Details

Protein: CE33197
Organism: Caenorhabditis elegans
Length: 472 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE33197.

Description E-value Query
Range
Subject
Range
gi|28300433, gi|... - gi|6754714|ref|NP_034939.1| matrix metallopeptidase 3 [Mus musculus], gi|54872|emb|CAA44860.1| trans...
400.0 [0..1] [471..3]

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Predicted Domain #1
Region A:
Residues: [1-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWPLFLLGII GVVSAGIPGT NGDIRQPNFQ KELMDEAKVY LFKFGYMIPE PHQNVKTIQE  60
   61 PSEKQTKDAL IRFQSAFLYY SSGDVDVPTQ AKMNEWRCAN NDMDKGQPIP PASKKELWTK 120
  121 KSLTYKVVNT PNTLSQAQIR SAAHEAFEQW TRASGFKFVE TTGATPDITI TFYDVPQSNL 180
  181 RIAGSASKPV NSHIILDKNQ EWAYKSQAPM GISLYHTLLH EIGHILGLPH TFYRGSIMHP 240
  241 IFKPVLLPHG TVDTVPNVDR LAIRKIYGLS SVDHSTPSSD VDRSKCPKHL DSVVAINDQE 300
  301 WLFFRSNKVY KLNNRKFVDS GRPIQQVFPR GPQFVNATVS SGPLTLLFVE RTIYGYEYDG 360
  361 VQFTEAPNYP KELHDRVLFY PQGAFPLNNG SVILLSGNVF ATYNVQQNAP SFLNDKNRYF 420
  421 PNLPEDIKSG IEKTQGFTDA YYMFDEATVS DYDMNSKQVL QLQNIPDFLK CT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.0
Match: 1su3A
Description: X-ray structure of human proMMP-1: New insights into collagenase action
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.33358263548929 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.99457783001146 bayes_pls_golite062009
fibronectin binding 4.88120744785295 bayes_pls_golite062009
endopeptidase activity 4.16532996235931 bayes_pls_golite062009
peptidyl-dipeptidase activity 4.09850817629179 bayes_pls_golite062009
metallopeptidase activity 3.94798058866011 bayes_pls_golite062009
hydrolase activity 3.86424959037326 bayes_pls_golite062009
bradykinin receptor binding 3.75764679027735 bayes_pls_golite062009
metalloendopeptidase activity 3.43236442601127 bayes_pls_golite062009
exopeptidase activity 2.07461908743946 bayes_pls_golite062009
receptor binding 2.07222569254168 bayes_pls_golite062009
low-density lipoprotein receptor binding 1.8532193155997 bayes_pls_golite062009
protein complex binding 1.73407494465529 bayes_pls_golite062009
lipoprotein receptor binding 1.70122256659368 bayes_pls_golite062009
integrin binding 1.58328929324965 bayes_pls_golite062009
protein binding 1.58118182554863 bayes_pls_golite062009
binding 1.55761777216628 bayes_pls_golite062009
growth factor activity 1.45186436100051 bayes_pls_golite062009
transporter activity 1.28982382930122 bayes_pls_golite062009
G-protein-coupled receptor binding 1.28944451245801 bayes_pls_golite062009
transmembrane transporter activity 1.0688261398267 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
substrate-specific transporter activity 0.798767221679673 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543737159152136 bayes_pls_golite062009
zinc ion binding 0.49304764842799 bayes_pls_golite062009
serine hydrolase activity 0.393080846858665 bayes_pls_golite062009
serine-type peptidase activity 0.374597710524442 bayes_pls_golite062009
serine-type endopeptidase activity 0.252655558968584 bayes_pls_golite062009
ion transmembrane transporter activity 0.241890854867053 bayes_pls_golite062009
aminopeptidase activity 0.21808506596674 bayes_pls_golite062009
signal transducer activity 0.120905338073793 bayes_pls_golite062009
molecular transducer activity 0.120905338073793 bayes_pls_golite062009
transition metal ion binding 0.0527296790035641 bayes_pls_golite062009
cytokine receptor binding 0.0255053415182105 bayes_pls_golite062009
heparin binding 0.0209467326072597 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle