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Catalysis of the hydrolysis of peptide bonds formed between L-amino acids. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: metalloendopeptidase activity
Acc: GO:0004222
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Synonyms:
  • metalloendoprotease activity
  • metalloendoproteinase activity
Proteins in PDR annotated with:
   This term: 670 [Search]
   Term or descendants: 670 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004222 - metalloendopeptidase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle