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View Structure Prediction Details

Protein: ubq-1
Organism: Caenorhabditis elegans
Length: 538 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ubq-1.

Description E-value Query
Range		 Subject
Range
gi|113423966 - gi|113423966|ref|XP_001132949.1| PREDICTED: similar to Ubiquitin-63E CG11624-PA, isoform A [Homo sap...
 801.0 [0..1] [532..162]

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Predicted Domain #1
Region A:
Residues: [1-74] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIFVKTLTG KTITLEVEAS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN  60
   61 IQKESTLHLV LRLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1yx5B
Description: Solution Structure of S5a UIM-1/Ubiquitin Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [75-158] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGMQIFVKTL TGKTITLEVE ASDTIENVKA KIQDKEGIPP DQQRLIFAGK QLEDGRTLSD  60
   61 YNIQKESTLH LVLRLRGGMQ IFVK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.77
Match: 1m94A
Description: Ubiquitin-like modifier protein hub1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.77976521481104 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.45825282569124 bayes_pls_golite062009
acid-amino acid ligase activity 6.82424077726436 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.78164148882937 bayes_pls_golite062009
structural constituent of ribosome 5.77326793355348 bayes_pls_golite062009
structural molecule activity 5.36311620867914 bayes_pls_golite062009
ligase activity 2.93949076291021 bayes_pls_golite062009
protein binding 2.78014377544701 bayes_pls_golite062009
binding 2.70872150536621 bayes_pls_golite062009
transcription regulator activity 2.23822335492051 bayes_pls_golite062009
cytoskeletal protein binding 2.11984570584255 bayes_pls_golite062009
tubulin binding 2.03607606145909 bayes_pls_golite062009
nucleic acid binding 2.02209816078273 bayes_pls_golite062009
DNA binding 1.8833926783115 bayes_pls_golite062009
microtubule binding 1.75926256048235 bayes_pls_golite062009
protein tag 1.64936739586738 bayes_pls_golite062009
receptor binding 1.07983643886476 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.04462787665591 bayes_pls_golite062009
hydrolase activity 0.633589926944629 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.624731467637361 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.549761413791307 bayes_pls_golite062009
kinase activity 0.520011006272513 bayes_pls_golite062009
SUMO ligase activity 0.469920108401949 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.426082194130922 bayes_pls_golite062009
RNA binding 0.3655923364304 bayes_pls_golite062009
protein kinase activity 0.336252604607827 bayes_pls_golite062009
peptidase inhibitor activity 0.270602640718893 bayes_pls_golite062009
endopeptidase inhibitor activity 0.181054590240182 bayes_pls_golite062009
enzyme binding 0.147520546067615 bayes_pls_golite062009
structure-specific DNA binding 0.0623044995795676 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [159-224] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLTGKTITLE VEASDTIENV KAKIQDKEGI PPDQQRLIFA GKQLEDGRTL SDYNIQKEST  60
   61 LHLVLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1a5rA
Description: STRUCTURE DETERMINATION OF THE SMALL UBIQUITIN-RELATED MODIFIER SUMO-1, NMR, 10 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [225-301] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRGGMQIFVK TLTGKTITLE VEASDTIENV KAKIQDKEGI PPDQQRLIFA GKQLEDGRTL  60
   61 SDYNIQKEST LHLVLRL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.12
Match: 2nvuI
Description: No description for 2nvuI was found.

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.77976521481104 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.45825282569124 bayes_pls_golite062009
acid-amino acid ligase activity 6.82424077726436 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.78164148882937 bayes_pls_golite062009
structural constituent of ribosome 5.77326793355348 bayes_pls_golite062009
structural molecule activity 5.36311620867914 bayes_pls_golite062009
ligase activity 2.93949076291021 bayes_pls_golite062009
protein binding 2.78014377544701 bayes_pls_golite062009
binding 2.70872150536621 bayes_pls_golite062009
transcription regulator activity 2.23822335492051 bayes_pls_golite062009
cytoskeletal protein binding 2.11984570584255 bayes_pls_golite062009
tubulin binding 2.03607606145909 bayes_pls_golite062009
nucleic acid binding 2.02209816078273 bayes_pls_golite062009
DNA binding 1.8833926783115 bayes_pls_golite062009
microtubule binding 1.75926256048235 bayes_pls_golite062009
protein tag 1.64936739586738 bayes_pls_golite062009
receptor binding 1.07983643886476 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.04462787665591 bayes_pls_golite062009
hydrolase activity 0.633589926944629 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.624731467637361 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.549761413791307 bayes_pls_golite062009
kinase activity 0.520011006272513 bayes_pls_golite062009
SUMO ligase activity 0.469920108401949 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.426082194130922 bayes_pls_golite062009
RNA binding 0.3655923364304 bayes_pls_golite062009
protein kinase activity 0.336252604607827 bayes_pls_golite062009
peptidase inhibitor activity 0.270602640718893 bayes_pls_golite062009
endopeptidase inhibitor activity 0.181054590240182 bayes_pls_golite062009
enzyme binding 0.147520546067615 bayes_pls_golite062009
structure-specific DNA binding 0.0623044995795676 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [302-473] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGGMQIFVKT LTGKTITLEV EASDTIENVK AKIQDKEGIP PDQQRLIFAG KQLEDGRTLS  60
   61 DYNIQKESTL HLVLRLRGGM QIFVKTLIGK TITLEVEASD TIENVKAKIQ DKEGIPPDQQ 120
  121 RLIFAGKQLE DGRTLSDYNI QKESTLHLVL RLRGGMQIFV KTLTGKTITL EV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.154902
Match: 1z2mA
Description: Crystal Structure of ISG15, the Interferon-Induced Ubiquitin Cross Reactive Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [474-538] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EASDTIENVK AKIQDKEGIP PDQQRLIFAG VYSSFGAPSQ RRYADLRQDF DWKNHHSRGR  60
   61 SFGHH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 1x1mA
Description: Solution Structure of the N-terminal Ubiquitin-like Domain in Mouse Ubiquitin-like Protein SB132
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 7.96815122865454 bayes_pls_golite062009
ubiquitin-protein ligase activity 7.5865326390755 bayes_pls_golite062009
acid-amino acid ligase activity 6.96506647680367 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.87890364671564 bayes_pls_golite062009
structural constituent of ribosome 5.80275625219016 bayes_pls_golite062009
structural molecule activity 5.37716040292459 bayes_pls_golite062009
ligase activity 2.98370000660434 bayes_pls_golite062009
protein binding 2.9188688008729 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
transcription regulator activity 2.21955949922709 bayes_pls_golite062009
tubulin binding 2.21127283188349 bayes_pls_golite062009
cytoskeletal protein binding 2.20811136250556 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
nucleic acid binding 1.9984951714209 bayes_pls_golite062009
microtubule binding 1.92602521631666 bayes_pls_golite062009
DNA binding 1.86539227646379 bayes_pls_golite062009
receptor binding 1.09091623056284 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.06193722939839 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.62324312069889 bayes_pls_golite062009
hydrolase activity 0.614233748923048 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
RNA binding 0.359926300264681 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
peptidase inhibitor activity 0.27796076785312 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
endopeptidase inhibitor activity 0.189489510504993 bayes_pls_golite062009
structure-specific DNA binding 0.0788219117963673 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle