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View Structure Prediction Details

Protein: csn-2
Organism: Caenorhabditis elegans
Length: 495 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csn-2.

Description E-value Query
Range
Subject
Range
gi|39589343, gi|... - gi|39589343|emb|CAE74372.1| Hypothetical protein CBG22097 [Caenorhabditis briggsae], gi|187021987|em...
gi|157745009 - gi|157745009|ref|XP_001667601.1| Hypothetical protein CBG22097 [Caenorhabditis briggsae AF16]
215.0 [0..14] [489..14]

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Predicted Domain #1
Region A:
Residues: [1-495]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDEYMDDDE DYGFEYEDDS GSEPDVDMEN QYYTAKGLRS DGKLDEAIKS FEKVLELEGE  60
   61 KGEWGFKALK QMIKITFGQN RLEKMLEYYR QLLTYIKSAV TKNYSEKSIN AILDYISTSR 120
  121 QMDLLQHFYE TTLDALKDAK NERLWFKTNT KLGKLFFDLH EFTKLEKIVK QLKVSCKNEQ 180
  181 GEEDQRKGTQ LLEIYALEIQ MYTEQKNNKA LKWVYELATQ AIHTKSAIPH PLILGTIREC 240
  241 GGKMHLRDGR FLDAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLIKSD INPFDSQEAK 300
  301 PFKNEPEIVA MTQMVQAYQD NDIQAFEQIM AAHQDSIMAD PFIREHTEEL MNNIRTQVLL 360
  361 RLIRPYTNVR ISYLSQKLKV SQKEVIHLLV DAILDDGLEA KINEESGMIE MPKNKKKMMV 420
  421 TSLVVPNAGD QGTTKSDSKP GTSSEPSTTT SVTSSILQGP PATSSCHQEL SMDGLRVWAE 480
  481 RIDSIQSNIG TRIKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.78419126863783 bayes_pls_golite062009
binding 2.71974493738804 bayes_pls_golite062009
transcription regulator activity 2.36571535004008 bayes_pls_golite062009
nucleic acid binding 2.03244296439384 bayes_pls_golite062009
DNA binding 1.95874073664777 bayes_pls_golite062009
small conjugating protein ligase activity 1.6361512508718 bayes_pls_golite062009
protein binding 1.6279032205159 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.51715099535911 bayes_pls_golite062009
transcription repressor activity 1.41858884169884 bayes_pls_golite062009
transcription factor activity 1.21805666483342 bayes_pls_golite062009
acid-amino acid ligase activity 0.956814399390664 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.562731406491727 bayes_pls_golite062009
transcription factor binding 0.518146612491969 bayes_pls_golite062009
transcription cofactor activity 0.30464889749774 bayes_pls_golite062009
transferase activity 0.127854220687373 bayes_pls_golite062009
transcription activator activity 0.0593768116971065 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle