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View Structure Prediction Details

Protein: CE18087
Organism: Caenorhabditis elegans
Length: 490 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18087.

Description E-value Query
Range
Subject
Range
gi|37222544, gi|... - gi|37681498|gb|AAP69599.1| glutathione synthetase [Lotus corniculatus var. japonicus], gi|37222544|g...
710.0 [0..1] [487..58]

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Predicted Domain #1
Region A:
Residues: [1-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKDDRILL LNAPRLPLED DKLNELTADL HDWAHANGLV MRLSTDKLSS EVCQTTPLTL  60
   61 LPSPFPKNVF EEAVHIQNLF ASLYHFIAYE FDFLIDIHKN VVKTDDFTRN MVEILKKVKA 120
  121 QGLKQPVTLA IQRSDYMCHK DQYSAEYGLK QIEINNIASS MGAHALRLTE WHIRVLKALN 180
  181 ISDDVIQRAI PENKPIPMIA EALFKAWSHF SNPAAVVLVV VENVNQNQID QRHVEYELEK 240
  241 LGVPMTCIIR RNLTQCYEQL SLNDRSDLMI DGRQVAIVYF RAGYSPDHYP STKEWEARER 300
  301 MELSTAIKTP WIGLQVANTK KTQQVLSEDG VLERFIGKPR EARDIRASFA GMWALENTDE 360
  361 VTMKVVAGAQ KHPEAFVLKP QTEGGAALHT GDEMVQMLRE LPEEERGAFI LMEKLKPMII 420
  421 ENYLVLAKKP ITFAKAVSEL GVYGYAFGRK DAPELKTAGH LLRTKPESTA MGGVAAGHAV 480
  481 VDTPFLYEFI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2hgsA
Description: Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutathione binding 3.43434843798286 bayes_pls_golite062009
ligase activity 3.25077459445999 bayes_pls_golite062009
glutathione synthase activity 3.18460876432532 bayes_pls_golite062009
catalytic activity 2.5009559386228 bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds 1.59015373957506 bayes_pls_golite062009
succinate-CoA ligase activity 1.52785506428706 bayes_pls_golite062009
CoA carboxylase activity 1.44257510787161 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 0.935432886482705 bayes_pls_golite062009
acetyl-CoA carboxylase activity 0.78189952793438 bayes_pls_golite062009
acid-amino acid ligase activity 0.599203164789408 bayes_pls_golite062009
CoA-ligase activity 0.51228075142462 bayes_pls_golite062009
acid-thiol ligase activity 0.448084116680826 bayes_pls_golite062009
binding 0.374385700553659 bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity 0.324506681366243 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.239594107637156 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle