YRC Public Data Repository - Protein Structure Prediction

Protein:	arl-5
Organism:	Caenorhabditis elegans
Length:	178 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arl-5.

Description	E-value	Query Range	Subject Range
gi\|34909214, gi\|... - gi\|34909214\|ref\|NP_915954.1\| putative ADP-ribosylation factor [Oryza sativa (japonica cultivar-group...	209.0	[0..1]	[178..179]
gi\|159131294 - gi\|159131294\|gb\|EDP56407.1\| ADP-ribosylation factor, putative [Aspergillus fumigatus A1163] gi\|70995568, gi\|... - gi\|70995568\|ref\|XP_752539.1\| ADP-ribosylation factor [Aspergillus fumigatus Af293], gi\|66850174\|gb\|E... gi\|41581249 - gi\|41581249\|emb\|CAE47898.1\| adp-ribosylation factor, putative [Aspergillus fumigatus] gi\|119412750, gi... - gi\|119495614\|ref\|XP_001264588.1\| ADP-ribosylation factor, putative [Neosartorya fischeri NRRL 181], ...	205.0	[0..1]	[178..1]
gi\|114197310, gi... - gi\|115491645\|ref\|XP_001210450.1\| ADP-ribosylation factor [Aspergillus terreus NIH2624], gi\|114197310...	205.0	[0..1]	[178..1]
gi\|83773942 - gi\|83773942\|dbj\|BAE64067.1\| unnamed protein product [Aspergillus oryzae] gi\|238498256, gi... - gi\|238498256\|ref\|XP_002380363.1\| ADP-ribosylation factor, putative [Aspergillus flavus NRRL3357], gi... gi\|169781474 - gi\|169781474\|ref\|XP_001825200.1\| hypothetical protein [Aspergillus oryzae RIB40]	204.0	[0..1]	[178..1]
gi\|46108264, gi\|... - gi\|46108264\|ref\|XP_381190.1\| ARF_AJECA ADP-RIBOSYLATION FACTOR [Gibberella zeae PH-1], gi\|42544974\|g...	204.0	[0..1]	[178..1]
gi\|49086430, gi\|... - gi\|67517899\|ref\|XP_658730.1\| ARF_AJECA ADP-RIBOSYLATION FACTOR [Aspergillus nidulans FGSC A4], ref\|X...	204.0	[0..1]	[178..1]
gi\|47026845 - gi\|47026845\|gb\|AAT08648.1\| ADP-ribosylation factor [Hyacinthus orientalis]	203.0	[0..1]	[178..19]
gi\|29028256 - gi\|29028256\|gb\|AAO62347.1\| ARF1-like GTP-binding protein [Gossypium hirsutum]	202.0	[0..1]	[178..1]
gi\|4056469, gi\|2... - gi\|4056469\|gb\|AAC98042.1\| Strong similarity to gb\|M95166 ADP-ribosylation factor from Arabidopsis th...	202.0	[0..1]	[178..1]
ARF1_SOLTU - ADP-ribosylation factor 1 OS=Solanum tuberosum PE=2 SV=2	202.0	[0..1]	[178..1]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLIMAKLFQ SWWIGKKYKI IVVGLDNAGK TTILYNYVTK DQVETKPTIG SNVEEVSYRN  60
   61 LDFVIWDIGG QESLRKSWST YYVQTDVVIV VIDSSDTTRI PIMKEQLHNM LQHEDLARAH 120
  121 ILVLANKQDL PGAMNPAEVS TQLGLQTLRG ARKWQINGCC AVKGEGLPEA LEWIANNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.39794
Match:	1r8qA
Description:	FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
microtubule motor activity	4.51968578934603	bayes_pls_golite062009
motor activity	4.04927796049806	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
structural constituent of muscle	2.82808660259595	bayes_pls_golite062009
tubulin binding	2.67743463093593	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
microtubule binding	2.59155206524122	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity	2.56769246638533	bayes_pls_golite062009
microfilament motor activity	2.51786963027655	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
cytoskeletal protein binding	2.4101693596493	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
actin binding	2.2973522188675	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
nucleic acid binding	2.09956015274464	bayes_pls_golite062009
transcription regulator activity	2.09345198747025	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
guanyl nucleotide binding	1.89320355239381	bayes_pls_golite062009
guanyl ribonucleotide binding	1.88721318481223	bayes_pls_golite062009
GTP binding	1.87900088157196	bayes_pls_golite062009
DNA binding	1.87765278833074	bayes_pls_golite062009
alpha-tubulin binding	1.792591628112	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.77111739879769	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	1.75695995185278	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
GTPase activity	1.6309422514633	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
signal recognition particle binding	1.46975774710831	bayes_pls_golite062009
plus-end-directed microtubule motor activity	1.38366133153678	bayes_pls_golite062009
microtubule plus-end binding	1.36713729043205	bayes_pls_golite062009
actin filament binding	1.28204719195916	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
RNA helicase activity	1.02424782546779	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATP binding	0.98146619596929	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
RNA-dependent ATPase activity	0.95986988363392	bayes_pls_golite062009
adenyl ribonucleotide binding	0.949788783884952	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.94128341275411	bayes_pls_golite062009
adenyl nucleotide binding	0.931486373329219	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
actin-dependent ATPase activity	0.92105578610354	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
kinase activity	0.691112783105676	bayes_pls_golite062009
molecular transducer activity	0.683309012097319	bayes_pls_golite062009
signal transducer activity	0.683309012097319	bayes_pls_golite062009
transcription factor activity	0.682439846757997	bayes_pls_golite062009
transmembrane receptor activity	0.661834961742057	bayes_pls_golite062009
beta-tubulin binding	0.654735466720932	bayes_pls_golite062009
receptor activity	0.633514002718998	bayes_pls_golite062009
amino acid transmembrane transporter activity	0.585668369219566	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
ribonucleoprotein binding	0.53788302029845	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.499834566483656	bayes_pls_golite062009
microtubule-severing ATPase activity	0.491769258942331	bayes_pls_golite062009
drug transmembrane transporter activity	0.38711726712063	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.305627755818843	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.213018989352421	bayes_pls_golite062009
structural constituent of ribosome	0.208665086324262	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009
cell surface binding	0.0454774504404609	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0430764033739892	bayes_pls_golite062009
protein kinase activity	0.0364322017534667	bayes_pls_golite062009
structural constituent of cytoskeleton	0.0111338193708552	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: