YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC16D10.08c
Organism:	Schizosaccharomyces pombe
Length:	905 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC16D10.08c.

Description	E-value	Query Range	Subject Range
CLPB_PASMU - Chaperone protein clpB OS=Pasteurella multocida GN=clpB PE=3 SV=1 CLPB_PASMU - Chaperone protein ClpB OS=Pasteurella multocida (strain Pm70) GN=clpB PE=3 SV=1	618.0	[0..1]	[875..1]
gi\|25289928 - pir\|\|AF3276 ATP-dependent clp proteinase, ATP-binding chain clpb BMEI0195 [imported] - Brucella meli... gi\|17986479, gi\|... - gi\|17986479\|ref\|NP_539113.1\| ATP-dependent Clp protease, ATP-binding subunit CLPB [Brucella melitens...	618.0	[0..1]	[895..58]
gi\|52307890, gi\|... - gi\|52425838\|ref\|YP_088975.1\| ClpA protein [Mannheimia succiniciproducens MBEL55E], gi\|52307890\|gb\|AA...	611.0	[0..1]	[877..1]
CLPB_BRUSU - Chaperone protein ClpB OS=Brucella suis biovar 1 (strain 1330) GN=clpB PE=2 SV=1 CLPB_BRUSU - Chaperone protein clpB OS=Brucella suis GN=clpB PE=2 SV=1	611.0	[0..1]	[895..1]
gi\|225853303, gi... - gi\|225853303\|ref\|YP_002733536.1\| ATP-dependent chaperone ClpB [Brucella melitensis ATCC 23457], gi\|2... CLPB_BRUME - Chaperone protein ClpB OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=cl... CLPB_BRUME - Chaperone protein clpB OS=Brucella melitensis GN=clpB PE=3 SV=2	610.0	[0..1]	[895..1]
gi\|56750469, gi\|... - gi\|56750469\|ref\|YP_171170.1\| ClpB protein [Synechococcus elongatus PCC 6301], gi\|56685428\|dbj\|BAD786...	609.0	[0..2]	[885..14]
gi\|254690013 - gi\|254690013\|ref\|ZP_05153267.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucella... gi\|254694504 - gi\|254694504\|ref\|ZP_05156332.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucella... gi\|62196857, gi\|... - gi\|62290725\|ref\|YP_222518.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucella ab... gi\|82700638 - gi\|82700638\|ref\|YP_415212.1\| chaperonin ClpA/B [Brucella melitensis biovar Abortus 2308] gi\|254696129 - gi\|254696129\|ref\|ZP_05157957.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucella... gi\|82616739 - gi\|82616739\|emb\|CAJ11824.1\| Chaperonin clpA/B:ATP/GTP-binding site motif A (P-loop):AAA ATPase:AAA A... gi\|254731047 - gi\|254731047\|ref\|ZP_05189625.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucella... gi\|189024937, gi... - gi\|189024937\|ref\|YP_001935705.1\| ClpB, ATP-dependent Clp protease, ATP-binding subunit ClpB [Brucell...	609.0	[0..1]	[895..1]
CLPB_GLOVI - Chaperone protein ClpB OS=Gloeobacter violaceus GN=clpB PE=3 SV=1 CLPB_GLOVI - Chaperone protein ClpB OS=Gloeobacter violaceus (strain PCC 7421) GN=clpB PE=3 SV=1	608.0	[0..2]	[877..5]
gi\|81299898, gi\|... - gi\|81299898\|ref\|YP_400106.1\| ATPase [Synechococcus elongatus PCC 7942], gi\|81168779\|gb\|ABB57119.1\| A...	608.0	[0..2]	[885..14]
gi\|21957649, gi\|... - gi\|22124822\|ref\|NP_668245.1\| protein disaggregation chaperone [Yersinia pestis KIM], gi\|21957649\|gb\|... gi\|45435364, gi\|... - gi\|45440507\|ref\|NP_992046.1\| protein disaggregation chaperone [Yersinia pestis biovar Microtus str. ...	608.0	[0..1]	[877..8]

Back

Predicted Domain #1

Region A:
Residues: [1-905]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADYPFTDKA AKTLSDAYSI AQSYGHSQLT PIHIAAALLS DSDSNGTTLL RTIVDKAGGD  60
   61 GQKFERSVTS RLVRLPAQDP PPEQVTLSPE SAKLLRNAHE LQKTQKDSYI AQDHFIAVFT 120
  121 KDDTLKSLLA EAGVTPKAFE FAVNNVRGNK RIDSKNAEEG FDALNKFTVD LTELARNGQL 180
  181 DPVIGREDEI RRTIRVLSRR TKNNPVLIGE PGVGKTSIAE GLARRIIDDD VPANLSNCKL 240
  241 LSLDVGSLVA GSKFRGEFEE RIKSVLKEVE ESETPIILFV DEMHLLMGAG SGGEGGMDAA 300
  301 NLLKPMLARG KLHCIGATTL AEYKKYIEKD AAFERRFQII LVKEPSIEDT ISILRGLKEK 360
  361 YEVHHGVTIS DRALVTAAHL ASRYLTSRRL PDSAIDLVDE AAAAVRVTRE SQPEVLDNLE 420
  421 RKLRQLRVEI RALEREKDEA SKERLKAARK EAEQVEEETR PIREKYELEK SRGSELQDAK 480
  481 RRLDELKAKA EDAERRNDFT LAADLKYYGI PDLQKRIEYL EQQKRKADAE AIANAQPGSE 540
  541 PLLIDVVGPD QINEIVARWT GIPVTRLKTT EKERLLNMEK VLSKQVIGQN EAVTAVANAI 600
  601 RLSRAGLSDP NQPIASFLFC GPSGTGKTLL TKALASFMFD DENAMIRIDM SEYMEKHSVS 660
  661 RLIGAPPGYV GHEAGGQLTE QLRRRPYSVI LFDEIEKAAP EVLTVLLQVL DDGRITSGQG 720
  721 QVVDAKNAVI IMTSNLGAEY LTTDNESDDG KIDSTTREMV MNSIRGFFRP EFLNRISSIV 780
  781 IFNRLRRVDI RNIVENRILE VQKRLQSNHR SIKIEVSDEA KDLLGSAGYS PAYGARPLNR 840
  841 VIQNQVLNPM AVLILNGQLR DKETAHVVVQ NGKIFVKPNH EANANGSADI DMDGIDDDVN 900
  901 DEELE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	160.0
Match:	1qvrA
Description:	Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.54081962055485	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.36181317078971	bayes_pls_golite062009
transmembrane transporter activity	3.29578916194335	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
hydrolase activity	2.55157966585974	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.32451967319952	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.20669061476179	bayes_pls_golite062009
ATPase activity, coupled	2.18396165590908	bayes_pls_golite062009
nucleic acid binding	2.11222585187695	bayes_pls_golite062009
DNA binding	1.7904783386531	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
transcription regulator activity	1.68903321260301	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.67543589693508	bayes_pls_golite062009
substrate-specific transporter activity	1.29730375126024	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
motor activity	0.87979065815418	bayes_pls_golite062009
structural constituent of ribosome	0.860102064846772	bayes_pls_golite062009
structure-specific DNA binding	0.762584163889896	bayes_pls_golite062009
DNA-dependent ATPase activity	0.75383985982414	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
transcription activator activity	0.638755032892208	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
transcription factor activity	0.603758349693077	bayes_pls_golite062009
double-stranded DNA binding	0.49000746592281	bayes_pls_golite062009
protein transmembrane transporter activity	0.46552249844591	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
ion transmembrane transporter activity	0.355466224802969	bayes_pls_golite062009
helicase activity	0.33971254173831	bayes_pls_golite062009
sequence-specific DNA binding	0.334630071828653	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
DNA strand annealing activity	0.270268254152179	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
signal recognition particle binding	0.20866768220789	bayes_pls_golite062009
microtubule motor activity	0.11674780318211	bayes_pls_golite062009
structural molecule activity	0.11239762372728	bayes_pls_golite062009
cation transmembrane transporter activity	0.0254369227200564	bayes_pls_golite062009
ATP-dependent helicase activity	0.0136700590511267	bayes_pls_golite062009
purine NTP-dependent helicase activity	0.0136700590511267	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: