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View Structure Prediction Details

Protein: dnm1
Organism: Schizosaccharomyces pombe
Length: 781 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnm1.

Description E-value Query
Range
Subject
Range
gi|76621599 - gi|76621599|ref|XP_886052.1| PREDICTED: similar to dynamin 2 isoform 27 [Bos taurus]
739.0 [0..1] [780..1]
DYN1_MOUSE - Dynamin-1 OS=Mus musculus GN=Dnm1 PE=1 SV=2
734.0 [0..1] [780..6]
gi|73986678 - gi|73986678|ref|XP_867956.1| PREDICTED: similar to dynamin 2 isoform 2 isoform 12 [Canis familiaris]
731.0 [0..1] [780..6]

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Predicted Domain #1
Region A:
Residues: [1-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQLIPLVNQ LQDLVYNTIG SDFLDLPSIV VVGSQSCGKS SVLENIVGKD FLPRGTGIVT  60
   61 RRPLILQLIN LKRKTKNNHD EESTSDNNSE ETSAAGETGS LEGIEEDSDE IEDYAEFLHI 120
  121 PDTKFTDMNK VRAEIENETL RVAGANKGIN KLPINLKIYS TRVLNLTLID LPGLTKIPVG 180
  181 DQPTDIEAQT RSLIMEYISR PNSIILAVSP ANFDIVNSEG LKLARSVDPK GKRTIGVLTK 240
  241 LDLMDQGTNA MDILSGRVYP LKLGFVATVN RSQSDIVSHK SMRDALQSER SFFEHHPAYR 300
  301 TIKDRCGTPY LAKTLSNLLV SHIRERLPDI KARLSTLISQ TQQQLNNYGD FK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.221849
Match: 1jwyB
Description: Dynamin G domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 6.13591371239337 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
plus-end-directed microtubule motor activity 2.65631438185675 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
microfilament motor activity 2.51786963027655 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
actin-dependent ATPase activity 0.92105578610354 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
molecular transducer activity 0.683309012097319 bayes_pls_golite062009
signal transducer activity 0.683309012097319 bayes_pls_golite062009
glutamate receptor binding 0.67946233728984 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
protein transporter activity 0.498432226280822 bayes_pls_golite062009
protein transmembrane transporter activity 0.46552249844591 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
signal recognition particle binding 0.29390189699022 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [353-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSDQSQRGII LLQAMNRFAN TFIASIDGNS SNIPTKELSG GARLYSIFNN VFTTALNSID  60
   61 PLQNLSTVDI RTAILNSTGS RATLFLSEMA FDILVKPQLN LLAAPCHQCV ELVYEELMKI 120
  121 CHYSGDSDIS HFPKLQTALV ETVSDLLREN LTPTYSFVES LIAIQSAYIN TNHPDFLGVQ 180
  181 GAMAVVLSRK EQNRLMLSQE NDEPISSALD TVKPDGIELY SSDPDTSVKS IT

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 44.638272
Match: PF01031.11
Description: No description for PF01031.11 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [585-685]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKATNEITTL KSDDSAKMQP LDVLASKRYN NAFSTETAER KTFLSYVFGA NNATRKAMSI  60
   61 DKSSSYPLND SLSGGDTNHK NNHPLKMTDL SNEVETMALE D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [686-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEREEVEVD LIKELITSYF NLTRKIIIDQ VPKVIMHLLV NASKDAIQNR LVSKLYREDF  60
   61 FDTLLIEDEN VKSEREKCER LLSVYNQANK IISTVF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 41.744727
Match: PF02212.9
Description: No description for PF02212.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.947 0.027 mitochondrial outer membrane a.47.2 t-snare proteins


YRC Informatics Platform - Version 3.0
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