YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: tup12
Organism: Schizosaccharomyces pombe
Length: 586 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tup12.

Description E-value Query
Range
Subject
Range
gi|23128312, gi|... - gi|23128312|ref|ZP_00110163.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668169...
433.0 [0..68] [582..598]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
428.0 [0..38] [585..959]
gi|35214926, gi|... - gi|37523920|ref|NP_927297.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
419.0 [0..43] [583..581]
gi|53764690, gi|... - gi|75908402|ref|YP_322698.1| peptidase C14, caspase catalytic subunit p20 [Anabaena variabilis ATCC ...
413.0 [0..66] [583..979]
gi|106891559, gi... - gi|148655047|ref|YP_001275252.1| WD-40 repeat-containing protein [Roseiflexus sp. RS-1], gi|14856715...
411.0 [0..76] [581..165]

Back

Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITVRQFTFT IFKFQFMATS NVSSRVNELL EAVKKEFEDI CQKTKTVEAQ KDDFEYKAMI  60
   61 SAQINEMALM KQTVMDLEMQ QSKVKDRYEE EITSLKAQLE ARRKEIASGV VPQSSKTKHG 120
  121 RNSVSF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.25
Match: 1jchA
Description: Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [127-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKYGNAGPFN SDNSSKPLIL NNGSSGGTPK NLRSPAIDSD GTVLAPIQTS NVDLGSQYYS  60
   61 SPHVRPAVGA TMAGSAMRTF PSNLPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [213-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHPPPPSDSA NSSVTPIAAP LVVNGKVSGN PPYPAEIIPT SNVPNREEKD WTVTSNVPNK  60
   61 EPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1crzA
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [276-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISVQLLHTLE HTSVICYVRF SADGKFLATG CNRAAMVFNV ETGKLITLLQ EESSKREGDL  60
   61 YVRSVAFSPD GKYLATGVED QQIRIWDIAQ KRVYRLLTGH EQEIYSLDFS KDGKTLVSGS 120
  121 GDRTVCLWDV EAGEQKLILH TDDGVTTVMF SPDGQFIAAG SLDKVIRIWT SSGTLVEQLH 180
  181 GHEESVYSVA FSPDGKYLVS GSLDNTIKLW ELQCVSNVAP SMYKEGGICK QTFTGHKDFI 240
  241 LSVTVSPDGK WIISGSKDRT IQFWSPDSPH SQLTLQGHNN SVISVAVSPN GHCFATGSGD 300
  301 LRARIWSYED L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.39794
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.67009948605948 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
myosin heavy chain kinase activity 4.33124151198369 bayes_pls_golite062009
GTPase activity 4.02994814377904 bayes_pls_golite062009
actin binding 3.86142918698875 bayes_pls_golite062009
acetyltransferase activity 3.85374902981345 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
myosin II binding 3.56132510021228 bayes_pls_golite062009
acyltransferase activity 3.35098520158193 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31615347567536 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.14917998298348 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.99343906593123 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
structural molecule activity 2.6914565031145 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
snoRNA binding 2.27164613239345 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
G-protein-coupled receptor binding 2.10926890165617 bayes_pls_golite062009
dynactin binding 2.07556426531897 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
receptor activity 1.69781740346574 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.5281054405163 bayes_pls_golite062009
kinase activity 1.5053563627859 bayes_pls_golite062009
telomerase activity 1.44665328127499 bayes_pls_golite062009
molecular transducer activity 1.42581655945599 bayes_pls_golite062009
signal transducer activity 1.42581655945599 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.33036729957356 bayes_pls_golite062009
protein kinase activity 1.3214585007945 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
RNA-directed DNA polymerase activity 1.10560669001943 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
type 1 angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
transferase activity 0.913674310517261 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription initiation factor activity 0.656824577987243 bayes_pls_golite062009
DNA-dependent ATPase activity 0.625780732991652 bayes_pls_golite062009
protein serine/threonine kinase activity 0.618638900707402 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
insulin receptor binding 0.43316396073854 bayes_pls_golite062009
peptide binding 0.387345823168967 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
nucleotidyltransferase activity 0.28606552120995 bayes_pls_golite062009
DNA helicase activity 0.220747580531792 bayes_pls_golite062009
enzyme regulator activity 0.161639372576406 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
kinase binding 0.0366162235750993 bayes_pls_golite062009
protein kinase binding 0.00858004043229577 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle