YRC Public Data Repository - Protein Structure Prediction

Protein:	ade7
Organism:	Schizosaccharomyces pombe
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ade7.

Description	E-value	Query Range	Subject Range
gi\|124894138, gi... - gi\|84362731\|ref\|ZP_00987345.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt...	391.0	[0..1]	[298..1]
gi\|78067425, gi\|... - gi\|78067425\|ref\|YP_370194.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ...	391.0	[0..1]	[298..1]
gi\|198037217, gi... - gi\|206561175\|ref\|YP_002231940.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholde... gi\|118707488, gi... - gi\|170733989\|ref\|YP_001765936.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholde... gi\|194558320, gi... - gi\|84355616\|ref\|ZP_00980493.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|116648734, gi... - gi\|67663919\|ref\|ZP_00461197.1\| SAICAR synthetase [Burkholderia cenocepacia HI2424], gi\|67102435\|gb\|E... gi\|67093431, gi\|... - gi\|67659007\|ref\|ZP_00456374.1\| SAICAR synthetase [Burkholderia cenocepacia AU 1054], gi\|67093431\|gb\|...	391.0	[0..1]	[298..1]
gi\|134139988, gi... - gi\|67548628\|ref\|ZP_00426513.1\| SAICAR synthetase [Burkholderia vietnamiensis G4], gi\|67530067\|gb\|EAM...	391.0	[0..1]	[298..1]
gi\|170697610, gi... - gi\|170697610\|ref\|ZP_02888699.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|115352723, gi... - gi\|74019294\|ref\|ZP_00689911.1\| SAICAR synthetase [Burkholderia ambifaria AMMD], gi\|72607968\|gb\|EAO43...	391.0	[0..1]	[298..1]
gi\|48785023, gi\|... - gi\|91785088\|ref\|YP_560294.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ...	387.0	[0..1]	[298..1]
gi\|67159243, gi\|... - gi\|67159243\|ref\|ZP_00419919.1\| SAICAR synthetase [Azotobacter vinelandii AvOP], gi\|67084272\|gb\|EAM03... gi\|67159243, gi\|... - gi\|67159243\|ref\|ZP_00419919.1\| SAICAR synthetase [Azotobacter vinelandii AvOP], ref\|ZP_00092957.1\| C...	385.0	[0..4]	[292..1]
gi\|126440287, gi... - gi\|67739194\|ref\|ZP_00489800.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|84523618, gi\|... - gi\|84523618\|ref\|ZP_01010754.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|126241803, gi... - gi\|67647398\|ref\|ZP_00445641.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|237502859, gi... - gi\|237811037\|ref\|YP_002895488.1\| phosphoribosylaminoimidazolesuccinocarboxamide synthase [Burkholder... gi\|254260906, gi... - gi\|90293040\|ref\|ZP_01212645.1\| hypothetical protein Bpse17_02002321 [Burkholderia pseudomallei 1710a... gi\|225928502, gi... - gi\|226199426\|ref\|ZP_03794984.1\| phosphoribosylaminoimidazolesuccinocarboxamide synthase [Burkholderi... gi\|85066664 - gi\|85066664\|ref\|ZP_01027517.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|87314519, gi\|... - gi\|87314519\|ref\|ZP_01095563.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|254187570, gi... - gi\|67753617\|ref\|ZP_00492547.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|67758817, gi\|... - gi\|67758817\|ref\|ZP_00497570.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|242138650, gi... - gi\|82536314\|ref\|ZP_00895321.1\| hypothetical protein Bpse110_02002372 [Burkholderia pseudomallei 1106... gi\|167901495 - gi\|167901495\|ref\|ZP_02488700.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|254203805, gi... - gi\|83618837\|ref\|ZP_00929286.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|167909741 - gi\|167909741\|ref\|ZP_02496832.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|167844508 - gi\|167844508\|ref\|ZP_02470016.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|82528909, gi\|... - gi\|82528909\|ref\|ZP_00888169.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|167893035 - gi\|167893035\|ref\|ZP_02480437.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|238522045, gi... - gi\|67641172\|ref\|ZP_00439956.1\| phosphoribosylaminoimidazolesuccinocarboxamide synthase [Burkholderia... gi\|254181612, gi... - gi\|99912105\|ref\|ZP_01318881.1\| hypothetical protein Bpse1_03001674 [Burkholderia pseudomallei 1655],... gi\|194526649, gi... - gi\|83623706\|ref\|ZP_00933969.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|167917763 - gi\|167917763\|ref\|ZP_02504854.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|100914161, gi... - gi\|67634577\|ref\|ZP_00433547.1\| COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synt... gi\|254176803, gi... - gi\|254176803\|ref\|ZP_04883460.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|124293409, gi... - gi\|124385389\|ref\|YP_001028388.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholde... gi\|167814475 - gi\|167814475\|ref\|ZP_02446155.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|167822940 - gi\|167822940\|ref\|ZP_02454411.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|243061681, gi... - gi\|243061681\|gb\|EES43867.1\| phosphoribosylaminoimidazolesuccinocarboxamide synthase [Burkholderia ma... gi\|167737352 - gi\|167737352\|ref\|ZP_02410126.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|52208852, gi\|... - gi\|53718438\|ref\|YP_107424.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ... gi\|52428462, gi\|... - gi\|53725039\|ref\|YP_102125.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ... gi\|76578525, gi\|... - gi\|76809072\|ref\|YP_332411.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ...	385.0	[0..1]	[295..1]
PUR7_METFK - Phosphoribosylaminoimidazole-succinocarboxamide synthase OS=Methylobacillus flagellatus (strain KT /...	384.0	[0..3]	[297..5]
gi\|167618049 - gi\|167618049\|ref\|ZP_02386680.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|167579979 - gi\|167579979\|ref\|ZP_02372853.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholder... gi\|83655246, gi\|... - gi\|83721421\|ref\|YP_441222.1\| phosphoribosylaminoimidazole-succinocarboxamide synthase [Burkholderia ...	384.0	[0..1]	[295..1]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALLKTSLDA PFTKIATGKV RDLYECVEFP DDLLFVATDR ISAYDFIMEN GIPEKGKVLT  60
   61 KISEFWFDVL KPHVQTHLIT SRWEELPPVI TKHEELKDRS MLVKKYKILP IEAIVRGYIT 120
  121 GSAWKEYQKQ GTVHGLNVPT GMKEAEAFPE PLFTPSTKAA EGHDENIHPD EVSKIVGPEL 180
  181 AKQVAETSVK LYKIARDVAL KKGIIIADTK FEFGVDETTN KIVLVDEVLT PDSSRFWLAS 240
  241 DYTVGKSPDS FDKQYLRNWL TANNLANKPN VSLPEDVVEA TRRKYVEAYE MITGKKWSY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	1a48A
Description:	SAICAR SYNTHASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	3.13563725397088	bayes_pls_golite062009
ligase activity	2.72434998554003	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.66954072457689	bayes_pls_golite062009
kinase activity	2.47933488612871	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.15276561572143	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.151446378007	bayes_pls_golite062009
catalytic activity	1.87792712964225	bayes_pls_golite062009
acid-amino acid ligase activity	1.8159520385203	bayes_pls_golite062009
binding	1.66593042987179	bayes_pls_golite062009
transferase activity	1.5866347320867	bayes_pls_golite062009
inositol or phosphatidylinositol kinase activity	1.35725237917644	bayes_pls_golite062009
lipid kinase activity	0.486217075920953	bayes_pls_golite062009
protein binding	0.382966234080422	bayes_pls_golite062009
protein kinase activity	0.135906673863896	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: