| Protein: | cmk2 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 504 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cmk2.
| Description | E-value | Query Range |
Subject Range |
|
|
297.0 | [0..61] | [504..10] |
|
|
296.0 | [0..61] | [504..10] |
|
|
296.0 | [0..10] | [500..27] |
|
|
294.0 | [0..16] | [500..36] |
|
|
290.0 | [0..2] | [500..19] |
|
|
287.0 | [0..61] | [504..10] |
|
Region A: Residues: [1-368] |
1 11 21 31 41 51
| | | | | |
1 MSILAGFKNL LKHSKSSKGR SNASKSVDVS VNRDVAAYTE LAAKNVNAGG DEEIRVANYP 60
61 GLEKYQLIEN LGDGAFSQVY KAYSIDRKEH VAVKVIRKYE MNKKQRQGVF KEVNIMRRVK 120
121 HKNVVNLFDF VETEDFYHLV MELAEGGELF HQIVNFTYFS ENLARHIIIQ VAEAVKHLHD 180
181 VCGIVHRDIK PENLLFQPIE YLPSQNYTPP SLEPNKLDEG MFLEGIGAGG IGRILIADFG 240
241 FSKVVWNSKT ATPCGTVGYA APEIVNDELY SKNVDMWAMG CVLHTMLCGF PPFFDENIKD 300
301 LASKVVNGEF EFLSPWWDDI SDSAKDLITH LLTVDPRERY DIHQFFQHPW IKGESKMPEN 360
361 FTYKPKLH
|
| Detection Method: |  |
| Confidence: | 61.30103 |
| Match: | 1a06A |
| Description: | CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| telethonin binding | 1.04264263421201 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| transcription repressor activity | 0.959888295228949 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transporter activity | 0.553953601841147 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.37676337669549 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.181804774839734 | bayes_pls_golite062009 |
| MAP kinase activity | 0.08504542461349 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0611721261859464 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
|
Region A: Residues: [369-504] |
1 11 21 31 41 51
| | | | | |
1 GTPGGPKLSL PRSLVSKGEI DIPTTPIKSA THPLLSSYSE PKTPGVSSVH EAMGVAYDIR 60
61 RLNHLGFSPE QLSKKSMNTG SIKELILDEE TTTDDDDYII SSFPLNDTLG SEGKDPFSLN 120
121 LKESSLYSRR SAKRVN
|
| Detection Method: | |
| Confidence: | 9.39794 |
| Match: | 1hkxA |
| Description: | Association donain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| calmodulin-dependent protein kinase activity | 3.94000509496614 | bayes_pls_golite062009 |
| nucleic acid binding | 2.55860381779056 | bayes_pls_golite062009 |
| binding | 2.52411158739487 | bayes_pls_golite062009 |
| protein binding | 2.39288962080451 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.08501421446176 | bayes_pls_golite062009 |
| protein transporter activity | 2.04189231186227 | bayes_pls_golite062009 |
| protein kinase activity | 2.00097234177267 | bayes_pls_golite062009 |
| kinase activity | 1.98914072004853 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.76679232625447 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 1.58752723298412 | bayes_pls_golite062009 |
| transferase activity | 1.27156008037861 | bayes_pls_golite062009 |
| transporter activity | 1.24263163723761 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 0.90194348627358 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.693314856519628 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.622032418966072 | bayes_pls_golite062009 |
| RNA binding | 0.47499792472996 | bayes_pls_golite062009 |
| structural molecule activity | 0.388035617388367 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.204604542884036 | bayes_pls_golite062009 |
| mRNA binding | 0.15644148341628 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.06886025448369 | bayes_pls_golite062009 |
| macromolecule transmembrane transporter activity | 0.06886025448369 | bayes_pls_golite062009 |
