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View Structure Prediction Details

Protein: FBpp0305074, FBp...
Organism: Drosophila melanogaster
Length: 503 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305074, FBp....

Description E-value Query
Range
Subject
Range
gi|66499593, gi|... - gi|66499600|ref|XP_623344.1| PREDICTED: similar to ariadne CG5659-PA, isoform A [Apis mellifera], gi...
361.0 [0..3] [503..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSDNDNDFC DNVDSGNVSS GDDGDDDFGM EVDLPSSADR QMDQDDYQYK VLTTDEIVQH  60
   61 QREIIDEANL LLKLPTPTTR ILLNHFKWDK EKLLEKYFDD NTDEFFKCAH VINP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNATEAIKQK TSRSQCEECE ICFSQLPPDS MAGLECGHRF CMPCWHEYLS TKIVAEGLGQ  60
   61 TISCAAHGCD ILV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 2ct2A
Description: Solution Structure of the RING domain of the Tripartite motif protein 32
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [188-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDVTVANLVT DARVRVKYQQ LITNSFVECN QLLRWCPSVD CTYAVKVPYA EPRRVHCKCG  60
   61 HVFCFACGEN WHDPVKCRWL KKWIKKCDDD SETSNWIAAN TKEC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.4
Match: 2ct7A
Description: Solution Structure of the IBR domain of the RING finger protein 31 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.25982737281228 bayes_pls_golite062009
small conjugating protein ligase activity 5.16068345159314 bayes_pls_golite062009
acid-amino acid ligase activity 4.24782814163304 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.79292110382407 bayes_pls_golite062009
binding 2.70912934275371 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.02238152139385 bayes_pls_golite062009
transcription regulator activity 0.911827807813353 bayes_pls_golite062009
ubiquitin-specific protease activity 0.821040441472875 bayes_pls_golite062009
transcription factor binding 0.769719546176331 bayes_pls_golite062009
nucleic acid binding 0.69956438716198 bayes_pls_golite062009
transcription repressor activity 0.451160479135532 bayes_pls_golite062009
ligase activity 0.424146907469434 bayes_pls_golite062009
DNA binding 0.369510087469936 bayes_pls_golite062009
cysteine-type peptidase activity 0.356312424125648 bayes_pls_golite062009
hydrolase activity 0.185228576891116 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
peptidase activity 0.107857202210184 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.0136579100966835 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [292-343]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRCSVTIEKD GGCNHMVCKN QNCKNEFCWV CLGSWEPHGS SWYNCNRYDE DE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 1wd2A
Description: Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.07217714843839 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
transcription regulator activity 0.943706743211193 bayes_pls_golite062009
transcription factor binding 0.90065892745057 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription repressor activity 0.517687629465752 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
DNA binding 0.365874679056682 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
hydrolase activity 0.156835837705934 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
peptidase activity 0.121357659741468 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [344-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKTARDAQEK LRSSLARYLH YYNRYMNHMQ SMKFENKLYA SVKQKMEEMQ QHNMSWIEVQ  60
   61 FLKKAVDILC QCRQTLMYTY VFAYYLKKNN QSMIFEDNQK DLESATEMLS EYLERDITSE 120
  121 NLADIKQKVQ DKYRYCEKRC SVLLKHVHEG YDKEWWEYTE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle