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View Structure Prediction Details

Protein: Aats-lys-PB, FBp...
Organism: Drosophila melanogaster
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Aats-lys-PB, FBp....

Description E-value Query
Range
Subject
Range
gi|195963321, gi... - gi|20072717|gb|AAH27356.1| Kars protein [Mus musculus], gi|195963321|ref|NP_001124340.1| lysyl-tRNA ...
579.0 [0..1] [605..1]

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Predicted Domain #1
Region A:
Residues: [1-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFARCALRTV QGSWPRCRYT GIQPLAAGFH VSAPQMEPSK QTKLELKRRL KAEQKAKEKA  60
   61 EKAAAAPAEN TAGKKKSSAA EEEEISPNEY FKLRSAAVQE LKRSPATDPY PHKFHVSSSL 120
  121 EDFIAKYENS LKEGETLENV KLSVAGRVHA IRESGAKLIF YDLRGEGVKV QVMASAKSYK 180
  181 SEADFEIDTS KLRRGDIIGV VGHPGKTKKG ELSVMPSEIK LLSPCLHMLP HLHFGLKDKE 240
  241 TRYRQRYLDL ILNNNVREKF QIRAKIISYV RQFLDRLGFL EIETPMMNMI AGGATAKPFV 300
  301 THHNDLKMDL FMRIAPELYH KMLVVGGLDR VYEIGRQFRN EGIDLTHNPE FTTCEFYMAY 360
  361 ADYADIMDIT EQLVSGMVKA IRGSYKVIYH PEGPEGPEQE LDFTPPFKRV SMIKTLEEKL 420
  421 QVKFPAADTF NSPETNQFLS QLCAKHQVEC PAPRTTARLL DKLVGEFIEE FCVNPTFICE 480
  481 HPQIMSPLAK YHRSIPGLTE RFELFVAKKE ICNAYTELND PVVQRERFEQ QASDKAAGDD 540
  541 EAQLVDENFC TSLEYGLPPT GGFGMGIDRL AMFLTDSNNI KEVLLFPAMK PEDANRTAAE 600
  601 TAPTAQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 148.0
Match: 1e1oA
Description: Lysyl-tRNA synthetase (LysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine-tRNA ligase activity 11.0047124677093 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
aspartate-tRNA ligase activity 3.80084837437429 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 3.4145644216516 bayes_pls_golite062009
structural constituent of ribosome 2.90150581291897 bayes_pls_golite062009
glycine-tRNA ligase activity 2.61548498770105 bayes_pls_golite062009
structural molecule activity 2.54582212334303 bayes_pls_golite062009
proline-tRNA ligase activity 2.52223115725965 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
translation initiation factor activity 1.27539679024898 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
binding 0.916222310895772 bayes_pls_golite062009
single-stranded DNA binding 0.56590887755068 bayes_pls_golite062009
ribonuclease activity 0.506819168662173 bayes_pls_golite062009
transcription regulator activity 0.375542987753806 bayes_pls_golite062009
nuclease activity 0.29926900436997 bayes_pls_golite062009
nucleic acid binding 0.281662799812287 bayes_pls_golite062009
DNA binding 0.0309732052586011 bayes_pls_golite062009

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