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View Structure Prediction Details

Protein: CG6255-PA
Organism: Drosophila melanogaster
Length: 342 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6255-PA.

Description E-value Query
Range
Subject
Range
gi|89289518, gi|... - gi|89289518|gb|EAR87506.1| succinyl-CoA synthetase, alpha subunit family protein [Tetrahymena thermo...
13203; - /numExons=5 /strand=+ /begin=949932 /end=952212 /seqFile=euttg.scaffolds.fasta /startCodon=0 /coords...
326.0 [0..19] [327..168]

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Predicted Domain #1
Region A:
Residues: [1-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNRGSKML LRALTPQILR RGKADYGKTV CNLKINKATK VLVQGFTGKQ ATFHSEESIK  60
   61 YGTNIVGGVN PKKGGTEHLG KPVFKSVAEA VEKAKPDATV IFIPPPSAAE GICAAIESEI 120
  121 GLIVAITEGI PQADMVRISQ MLNCQEKSRL LGPNCPGIIS PDQCKIGIMP GDIHKRGVVG 180
  181 IVSRSGTLTY ESVHQTTNVG LGQALCVGLG GDPFNGTSFI DALKVFLSDK EIKGIVMIGE 240
  241 IGGSAEEEAA DFLKEKNTGC EAKPVVGFIA GQTAPPGRRM GHAGAIISGG KGAAKDKVAA 300
  301 LEKAGVRMTA NPCHLGSTLL EEMIRLKLVP KPNKKKAQAG KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.69897
Match: 1jkjA
Description: Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain; Succinyl-CoA synthetase, alpha-chain, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
succinate-CoA ligase activity 11.5979130191209 bayes_pls_golite062009
succinate-CoA ligase (GDP-forming) activity 10.9659410855563 bayes_pls_golite062009
CoA-ligase activity 10.4192804448897 bayes_pls_golite062009
acid-thiol ligase activity 10.243481928473 bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds 9.48706872092269 bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity 9.35325976720833 bayes_pls_golite062009
malate dehydrogenase activity 4.38786524125089 bayes_pls_golite062009
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 3.07329302783164 bayes_pls_golite062009
ligase activity 2.30626698552338 bayes_pls_golite062009
catalytic activity 1.90735517755117 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 1.70038641098437 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
malic enzyme activity 1.2147813077436 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.15639517822408 bayes_pls_golite062009
L-malate dehydrogenase activity 1.02646414923682 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.99118526697655 bayes_pls_golite062009
ATP citrate synthase activity 0.917482134347073 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.576163737662951 bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 0.120195861875768 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.0913823272876781 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.00644214957417527 bayes_pls_golite062009

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