| Protein: | Csk-PI, Csk-PK, ... |
| Organism: | Drosophila melanogaster |
| Length: | 723 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Csk-PI, Csk-PK, ....
| Description | E-value | Query Range |
Subject Range |
|
|
441.0 | [0..1] | [723..83] |
|
Region A: Residues: [1-100] |
1 11 21 31 41 51
| | | | | |
1 MNSHATATQN GQTTVVGHHR GFSQPSVTVA AAAATGSTAG DPWFLQTTGH QMPPTAPLRH 60
61 NKRPAPQPNA VLGAGSSGTA PGSAVGAVLL HQQQLSQSQP
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [101-273] |
1 11 21 31 41 51
| | | | | |
1 HIVPPSIPPH HHHHRENNVH PIQAGAAAAL HLSSHALNSH NLISSASNHS PKSPSQTQQQ 60
61 QQTTNQQQQQ QQQQASHSIL STFAPAPTVA AVQPAGSQSV AGTAAAVAAV AQQQQQQHLQ 120
121 LLANCPPGGA GLMSSSLNAA QMGMHGAERA LPPKSLALSG SQHGSNMLLH TAP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [274-723] |
1 11 21 31 41 51
| | | | | |
1 QPPQASQPAA VVGVSGSGSA GMSTSLHSFD INGVTAGSGV NASSAWSSGS TTAMNHASLS 60
61 PTALAPQQGR SRCEVKLNAM PWFHGSITRD EAEHLLQPRE DGLFLVREST NFPGDYTLCV 120
121 CFQSKVEHYR VKYLENKLTI DDEEYFENLG QLVAHYEADA DGLCTQLIKC LPKLGKQEFC 180
181 INSKDFVDKG WVIPEAELQL RESIGKGEFG DVMLGILRNE KVAVKMLKDE GAVQKFLAEA 240
241 SVMTTLEHDN LVKFIGLVFT SKHLYLVTEY MSKGSLVDYL RSRGRQHITK KDQIIFAYDT 300
301 ASGMEYLEAK KVVHRDLAAR NVLISEDCVA KVSDFGLARE ECYNLDVGKL PIKWTAPEAL 360
361 KNGRFSNKSD MWSFGILLWE IYSFGRVPYP RIPLADVVKH VEVGYKMEAP EGCPPEIYEM 420
421 MRQAWDLNPA KRPTFAELKV KLQLLNNATA
|
| Detection Method: | |
| Confidence: | 92.69897 |
| Match: | 1k9aA |
| Description: | Carboxyl-terminal src kinase (csk) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 4.41722924924158 | bayes_pls_golite062009 |
| actin binding | 3.91045208670052 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| CD8 receptor binding | 3.34636716492159 | bayes_pls_golite062009 |
| protein binding | 3.19631993182765 | bayes_pls_golite062009 |
| molecular transducer activity | 3.13508395312263 | bayes_pls_golite062009 |
| signal transducer activity | 3.13508395312263 | bayes_pls_golite062009 |
| binding | 3.12724619324809 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| insulin receptor binding | 2.73485644242393 | bayes_pls_golite062009 |
| actin filament binding | 2.72908433443928 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.65451266834284 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.4913932444423 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.85015570449703 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| kinase activity | 1.78069536883109 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.59739467025045 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| PTB domain binding | 1.56656184134104 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| receptor binding | 1.52843393025918 | bayes_pls_golite062009 |
| protein kinase activity | 1.4654611643382 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| transporter activity | 1.30447542854757 | bayes_pls_golite062009 |
| transferase activity | 1.19152443245584 | bayes_pls_golite062009 |
| tubulin binding | 1.13686658158825 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| SH2 domain binding | 1.09679619057368 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.08558010881058 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| structural molecule activity | 0.989403012920596 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.820987609295422 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| microtubule binding | 0.734274677384472 | bayes_pls_golite062009 |
| protein complex binding | 0.65988681496356 | bayes_pls_golite062009 |
| protein phosphorylated amino acid binding | 0.649814096718101 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
| insulin binding | 0.546269851452869 | bayes_pls_golite062009 |
| transcription regulator activity | 0.540818657754841 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.52430033936893 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| nucleic acid binding | 0.476094076158571 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.371928447183203 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| DNA binding | 0.281643350069021 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.206747304356052 | bayes_pls_golite062009 |
| insulin receptor activity | 0.188254408239569 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.169458153875562 | bayes_pls_golite062009 |
| phosphoprotein binding | 0.16798254471727 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.16478124520484 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| kinase regulator activity | 0.10704587503284 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 0.0613131034808199 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.0443241110585009 | bayes_pls_golite062009 |
