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View Structure Prediction Details

Protein: Gpo-1-PD, Gpo-1-...
Organism: Drosophila melanogaster
Length: 724 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gpo-1-PD, Gpo-1-....

Description E-value Query
Range
Subject
Range
gi|125812000|ref... - GA20935-PA [Drosophila pseudoobscura], GA20935 [Drosophila pseudoobscura pseudoobscura]
gi|125812000, gi... - gi|54637252|gb|EAL26655.1| GA20935 [Drosophila pseudoobscura pseudoobscura], gi|125812000|ref|XP_001...
gi|195171751, gi... - gi|195171751|ref|XP_002026667.1| GL11848 [Drosophila persimilis], gi|194111593|gb|EDW33636.1| GL1184...
442.0 [0..1] [724..1]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSRMFKFGV TAASACVGSV LASYTLDRWN TPHVVNNATV PPKRKRTLPP RADQIKSLMS  60
   61 GEEFDVLII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 2braA
Description: Structure of N-Terminal FAD Binding motif of mouse MICAL
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [70-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGATGAGCA LDSVTRGLKT ALVELDDFAS GTSSRSTKLI HGGVRYLQKA ILGLDLEQYR  60
   61 MVKEALAERA TMLESAPHLT HPLPIMLPVY TWWQVPYYWV GIKAYDLVAG DRNVKSSYYL 120
  121 SKKDALELFP MLKKDKLCGA IVYYDGQQDD ARMCLAVALT AARHGATVCN HVEVKELLKK 180
  181 DDGTGKQVLC GAKVKDHISG KEFTVKAKCI VNAAGPFTDS IRKMDNPTVK SICCPSSGVH 240
  241 IVLPGYYSPD QMGLLDPSTS DGRVIFFLPW QRQTIAGTTD LPCEITHNPT PTEDEIQFIL 300
  301 NEIKNYLNAD VEVRRGDVLS AWSGIRPLVS DPNKDDTQSL ARNHIVHVSP SNLITIAGGK 360
  361 WTTYRAMAEH TIDAAIKACN LKPERAEAVT SYLKIEGGQG WTPTMYIRLV QDFGLECEVA 420
  421 QHLAKSYGDR AFAVSKMASL TGKRWPIIGN RIHPEFPYID AEIRYGVREY ACTAVDMIAR 480
  481 RL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 1pj5A
Description: Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on NADH or NADPH 5.26950448055146 bayes_pls_golite062009
oxidoreductase activity 2.3417445147889 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 2.25002926602325 bayes_pls_golite062009
electron-transferring-flavoprotein dehydrogenase activity 1.55451764082771 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 1.45104542724719 bayes_pls_golite062009
transporter activity 1.29839290134235 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.18990628739838 bayes_pls_golite062009
antioxidant activity 1.12347155061135 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1.08975609376408 bayes_pls_golite062009
transmembrane transporter activity 1.07862908893913 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 0.955909900559292 bayes_pls_golite062009
binding 0.850689563354756 bayes_pls_golite062009
substrate-specific transporter activity 0.811783414198063 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 0.69501605197281 bayes_pls_golite062009
NADPH-adrenodoxin reductase activity 0.573803337547311 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.55964362614766 bayes_pls_golite062009
pyruvate dehydrogenase activity 0.494423552127166 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors 0.442625746935807 bayes_pls_golite062009
protein binding 0.370064403093958 bayes_pls_golite062009
ion transmembrane transporter activity 0.262741975112034 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.224438371728402 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.164825358655637 bayes_pls_golite062009
nucleic acid binding 0.162130833238942 bayes_pls_golite062009
amine oxidase activity 0.0576694782267841 bayes_pls_golite062009
cation transmembrane transporter activity 0.057221373695437 bayes_pls_golite062009
DNA binding 0.022476246602636 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [552-724]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLAFLNVQAA QEALPVIVDI MGEELGWSKD EKERQIKHAT EFLANEMGHS VNRTSKERIP  60
   61 IKLSKEEIQT YIKRFQLIDK DKKGYVSIND IRRALKSFGD GDVSGEQLHE ILREIDTNMN 120
  121 GQVELDEYLQ MMSAIKTGDV AYSRFARMAE LEEQKHEAAN LKQISVDRSG GGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.09691
Match: 1mxeA
Description: Calmodulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.30946149202257 bayes_pls_golite062009
protein binding 1.18539140568889 bayes_pls_golite062009
transporter activity 1.15928534291452 bayes_pls_golite062009
calcium ion binding 1.03474411638676 bayes_pls_golite062009
transmembrane transporter activity 0.945691505472547 bayes_pls_golite062009
ion binding 0.882500417315612 bayes_pls_golite062009
cation binding 0.87665890173512 bayes_pls_golite062009
metal ion binding 0.87665890173512 bayes_pls_golite062009
substrate-specific transporter activity 0.693724160233023 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.45412801027969 bayes_pls_golite062009
active transmembrane transporter activity 0.246383459363256 bayes_pls_golite062009
cytoskeletal protein binding 0.2350628837209 bayes_pls_golite062009
ion transmembrane transporter activity 0.193201281459889 bayes_pls_golite062009
motor activity 0.0886596083402598 bayes_pls_golite062009
cation transmembrane transporter activity 0.0305250212662123 bayes_pls_golite062009
molecular transducer activity 0.0215587845132821 bayes_pls_golite062009
signal transducer activity 0.0215587845132821 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle