YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CG12129-PA
Organism: Drosophila melanogaster
Length: 352 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG12129-PA.

Description E-value Query
Range
Subject
Range
gi|125808294, gi... - gi|54635871|gb|EAL25274.1| GA11423 [Drosophila pseudoobscura pseudoobscura], gi|125808294|ref|XP_001...
gi|54635871|gb|E... - GA11423-PA [Drosophila pseudoobscura], GA11423 [Drosophila pseudoobscura pseudoobscura]
187.0 [0..1] [352..1]

Back

Predicted Domain #1
Region A:
Residues: [1-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSREVLSPPV QKMSQNRRYR VNVVHDDFGG DKWNGQNQRN KLEYKAYEEP DLYGDDDDDE  60
   61 DDAVVKCIKE SANGDFSLSI HVSKSFYGGL IGMKGSTKRR IEEETRTEIF VPRPNDRSNE 120
  121 VTIKAKQRSQ VCAALRQIHH LVASLRKKMK PTHFLAVALN SGEVKERFME LKKCILEAEL 180
  181 PGIDKELFTP ECCIHLTLGV YVLLDDIERQ EALKNLESCR RLLDGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.34763707358864 bayes_pls_golite062009
nucleic acid binding 2.24838127771592 bayes_pls_golite062009
DNA binding 2.02012288821639 bayes_pls_golite062009
binding 1.9759530321894 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
structural constituent of ribosome 1.62566906146573 bayes_pls_golite062009
transcription termination factor activity 1.37964248399809 bayes_pls_golite062009
structural molecule activity 1.30244482268813 bayes_pls_golite062009
RNA polymerase activity 1.19766815287926 bayes_pls_golite062009
DNA-directed RNA polymerase activity 1.19766815287926 bayes_pls_golite062009
transcription factor activity 1.14242112812892 bayes_pls_golite062009
sequence-specific DNA binding 0.85691075793641 bayes_pls_golite062009
ribonuclease activity 0.62994126331969 bayes_pls_golite062009
protein binding 0.523813050066193 bayes_pls_golite062009
translation regulator activity 0.515576958825022 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.468402630523277 bayes_pls_golite062009
RNA binding 0.24714225183821 bayes_pls_golite062009
translation initiation factor activity 0.2080607201312 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transcription factor binding 0.0761113004281331 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [227-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIPFQIKVKG LEIMNDDPSS TRILYARIES PDLQKFADQC LAHFQTTALC ATDNIERESI  60
   61 KLHMTVMNNR YRNKANKSGN SFDAREILKR FGDFDFGVAQ CQAVHLCVLN SRSEDEFYKI 120
  121 SGSLEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.154902
Match: 1vdxA
Description: Crystal Structure of a Pyrococcus horikoshii protein with similarities to 2'5' RNA-ligase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle