| Protein: | Pkn-PC |
| Organism: | Drosophila melanogaster |
| Length: | 1407 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pkn-PC.
| Description | E-value | Query Range |
Subject Range |
|
|
1032.0 | [0..5] | [1407..20] |
|
Region A: Residues: [1-352] |
1 11 21 31 41 51
| | | | | |
1 MSDSYYQGEY IKHPVLYELS HKYGFTENLP ESCMSIRLEE IKEAIRREIR KELKIKEGAE 60
61 KLREVAKDRR SLSDVAVLVK KSKSKLAELK SELQELESQI LLTSANTAVN SNGQESITAC 120
121 IDPNGGFLVS GAVGGLGGGN TALEGGAPAT ANDKVLASLE KQLQIEMKVK TGAENMIQSL 180
181 GIGCDKKLLA EAHQMLADSK AKIEFLRLRI IKVKQNREQA DRLKASRQMI DEHGQTIGGN 240
241 NSSQPQSLET TLEERIEELR HRLRIEAAVV DGAKNVIRTL QTANRAPDKK ALQEAHGRLS 300
301 ESSRKLDLLR YSLDLRRQEL PADSPAAQQL KTELQIVQLS TSPAPVTYTS LQ
|
| Detection Method: |  |
| Confidence: | 24.045757 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [353-578] |
1 11 21 31 41 51
| | | | | |
1 SGQAGILGGK PYQSVSSLGR CASVTGKLEV RLLGCQDLLE DVPGRSRRDK DNNSSPGDLR 60
61 SFVKGVTSRS SSKSYSVKDE TSIEIMAVIK LDNITVGQTS WKQCSQQAWD QRFSIDLDRS 120
121 RELEIGVYWR DWRSLCAVKV LRLEEFIDDV RHGMALQLEP QGLLFAEVKF LNPMISQKPK 180
181 LRRQRMIFNR QQAKNISRAK QMNINVATWG RLLKRNAPNH VHMGSA
|
| Detection Method: | |
| Confidence: | 2.9 |
| Match: | 2fk9A |
| Description: | Human protein kinase C, eta |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [579-772] |
1 11 21 31 41 51
| | | | | |
1 GSGSSLTGSS PMVVGGSRDS ESPISRTPSS DALVEPEPYT PGEQAQNLEF DPDAGINEHV 60
61 ETPGEYPDPA ASGLSGMRPL SMHMQGISVL PPESPPVATG AAGRPNTLSL QMPGASKGQV 120
121 IQGGRTAAPT TAPPPPPVLK ATSTTPILDQ ELQDALHEFD FLSDLDSRPT TLRRLLKEQK 180
181 MALDAGALEN LLLQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [773-1341] |
1 11 21 31 41 51
| | | | | |
1 QQQTEQQALQ QRQRQEQLRL QQFQEAQRQA ILDLCVKQRE PAEQTSPTLA NQTPTFPPLA 60
61 SNQIMPSLNA RPCQSQSPNH NEFQLQPQPP HPAQKPTNPE PPSAVEQQLH RPVLILPPVV 120
121 LLGGREEDRS VPPSPLVEYP EDDDEYLYRG SNENLGTRLH SSHSSSAGDR FCVEVIPQLG 180
181 KLYVGSSQQQ YAQQSSPIIQ EPATPTIYGN SAAAGAPQFP QPAQRQEKQP PQQQPIYANQ 240
241 YELNVAKAAA AASVYSPSSS TTSNSNQQQQ QQRRNVARGL QYRESGGLET GRAGKQPPNA 300
301 GMLSMDNFRL LSVLGRGHFG KVILSQLRSN NQYYAIKALK KGDIIARDEV ESLLSEKRIF 360
361 EVANAMRHPF LVNLYSCFQT EQHVCFVMEY AAGGDLMMHI HTDVFLEPRA VFYAACVVLG 420
421 LQYLHENKII YRDLKLDNLL LDTEGYVKIA DFGLCKEGMG FGDRTGTFCG TPEFLAPEVL 480
481 TETSYTRAVD WWGLGVLIFE MLVGESPFPG DDEEEVFDSI VNDEVRYPRF LSLEAIAVMR 540
541 RLLRKNPERR LGSSERDAED VKKQAFFRS
|
| Detection Method: | |
| Confidence: | 55.0 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| acetylcholine receptor activator activity | 1.83545227594542 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.25765701903393 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.02996109010965 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 0.688047400629641 | bayes_pls_golite062009 |
| vinculin binding | 0.666656406096231 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| receptor binding | 0.197402253061255 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.0405961152540697 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [1342-1407] |
1 11 21 31 41 51
| | | | | |
1 IVWDDLLLRK VKPPFVPTIN HLEDVSNFDE EFTSEKAQLT PPKEPRHLTE EEQLLFQDFS 60
61 YTAEWC
|
| Detection Method: | |
| Confidence: | 105.0 |
| Match: | 2jdoA |
| Description: | No description for 2jdoA was found. |
