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View Structure Prediction Details

Protein: RBX1_MOUSE
Organism: Mus musculus
Length: 108 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBX1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|50728692 - gi|50728692|ref|XP_416239.1| PREDICTED: similar to RBX1 protein [Gallus gallus]
3.0E-25 [1..108] [252..359]
gi|78394982 - gi|78394982|gb|AAI07832.1| Rbx1 protein [Danio rerio]
4.0E-24 [1..108] [15..122]
gi|19067884, gi|... - gi|62869880|gb|AAY18085.1| hyperosmotic protein 21 [Salmo salar], gi|62869878|gb|AAY18084.1| hyperos...
5.0E-24 [1..108] [82..189]
gi|12833653 - gi|12833653|dbj|BAB22612.1| unnamed protein product [Mus musculus]
1.0E-23 [1..108] [1..108]
gi|114686561 - gi|114686561|ref|XP_001167997.1| PREDICTED: similar to RBX1 protein isoform 3 [Pan troglodytes]
1.0E-23 [1..108] [1..108]
gi|47208730 - gi|47208730|emb|CAF93382.1| unnamed protein product [Tetraodon nigroviridis]
3.0E-23 [1..108] [1..108]
gi|57092733 - gi|57092733|ref|XP_531722.1| PREDICTED: similar to RING-box protein 1 (Rbx1) [Canis familiaris]
3.0E-23 [1..105] [101..205]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM DLCIECQANQ  60
   61 ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE WEFQKYGH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 1u6gB
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 10.2497392096259 bayes_pls_golite062009
small conjugating protein ligase activity 10.0460587929138 bayes_pls_golite062009
acid-amino acid ligase activity 8.99384576623969 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 7.6988425139962 bayes_pls_golite062009
NEDD8 ligase activity 5.61847630780351 bayes_pls_golite062009
ligase activity 3.92677358871643 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
protein binding 1.5975811408548 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
transcription regulator activity 0.943706743211193 bayes_pls_golite062009
transcription factor binding 0.90065892745057 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
SUMO polymer binding 0.417597867824941 bayes_pls_golite062009
transcription repressor activity 0.393708074680332 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.392372133643049 bayes_pls_golite062009
DNA binding 0.365874679056682 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
enzyme binding 0.104373352314595 bayes_pls_golite062009

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