YRC Public Data Repository - Protein Structure Prediction

Protein:	APC11_MOUSE
Organism:	Mus musculus
Length:	84 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC11_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|50728692 - gi\|50728692\|ref\|XP_416239.1\| PREDICTED: similar to RBX1 protein [Gallus gallus]	94.0	[0..2]	[84..272]
gi\|76656847 - gi\|76656847\|ref\|XP_871863.1\| PREDICTED: similar to anaphase promoting complex subunit 11 homolog [Bo...	92.0	[0..7]	[84..124]
gi\|57092733 - gi\|57092733\|ref\|XP_531722.1\| PREDICTED: similar to RING-box protein 1 (Rbx1) [Canis familiaris]	91.0	[0..2]	[84..121]
gi\|113427199, gi... - gi\|113427201\|ref\|XP_001133297.1\| PREDICTED: similar to APC11 anaphase promoting complex subunit 11 i...	91.0	[0..1]	[80..1]
gi\|116200598, gi... - gi\|88175558\|gb\|EAQ83026.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11620...	88.0	[0..1]	[81..1]
gi\|85857156 - gi\|85857156\|dbj\|BAE78584.1\| anaphase-promoting complex subunit apc11 [Carassius auratus]	88.0	[0..1]	[84..1]
gi\|169153867, gi... - gi\|68436155\|ref\|XP_708405.1\| PREDICTED: hypothetical protein isoform 2 [Danio rerio], gi\|68436153\|re...	88.0	[0..1]	[84..1]
gi\|91080873 - gi\|91080873\|ref\|XP_972421.1\| PREDICTED: similar to anaphase promoting complex subunit 11 [Tribolium ...	87.0	[0..1]	[82..1]
gi\|19067884, gi\|... - gi\|62869880\|gb\|AAY18085.1\| hyperosmotic protein 21 [Salmo salar], gi\|62869878\|gb\|AAY18084.1\| hyperos...	87.0	[0..2]	[84..102]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVKIKCWNG VATWLWVAND ENCGICRMAF NGCCPDCKVP GDDCPLVWGQ CSHCFHMHCI  60
   61 LKWLNAQQVQ QHCPMCRQEW KFKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.522879
Match:	1u6gB
Description:	Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	10.2497392096259	bayes_pls_golite062009
small conjugating protein ligase activity	10.0460587929138	bayes_pls_golite062009
acid-amino acid ligase activity	8.99384576623969	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	7.6988425139962	bayes_pls_golite062009
ligase activity	3.92677358871643	bayes_pls_golite062009
binding	2.58862749918018	bayes_pls_golite062009
NEDD8 ligase activity	2.41658628840288	bayes_pls_golite062009
protein binding	1.49775478023418	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
transcription regulator activity	0.681643203460463	bayes_pls_golite062009
hydrolase activity	0.52386813728704	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.392372133643049	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
DNA binding	0.227671243150662	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
enzyme binding	0.104373352314595	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: