YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|56203342, gi\|...
Organism:	Homo sapiens
Length:	339 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56203342, gi|....

Description	E-value	Query Range	Subject Range
gi\|109092586 - gi\|109092586\|ref\|XP_001113090.1\| PREDICTED: similar to p47 protein isoform b isoform 2 [Macaca mulat...	1.0E-97	[1..339]	[1..339]
gi\|114680499 - gi\|114680499\|ref\|XP_001153718.1\| PREDICTED: p47 protein isoform 1 [Pan troglodytes]	8.0E-96	[1..339]	[1..341]
NSF1C_RAT - NSFL1 cofactor p47 OS=Rattus norvegicus GN=Nsfl1c PE=1 SV=1	2.0E-93	[1..339]	[1..370]
NSF1C_MOUSE - NSFL1 cofactor p47 OS=Mus musculus GN=Nsfl1c PE=1 SV=1	3.0E-93	[1..339]	[1..370]
NSF1C_BOVIN - NSFL1 cofactor p47 OS=Bos taurus GN=NSFL1C PE=2 SV=1	2.0E-92	[1..339]	[1..370]
gi\|123993027, gi... - gi\|124000007\|gb\|ABM87512.1\| NSFL1 (p97) cofactor (p47) [synthetic construct], gi\|123993027\|gb\|ABM841... NSF1C_PONAB - NSFL1 cofactor p47 OS=Pongo abelii GN=NSFL1C PE=2 SV=1 NSFL1C - NSFL1 (p97) cofactor (p47) NSF1C_PONPY - NSFL1 cofactor p47 - Pongo pygmaeus (Orangutan) gi\|114680495, gi... - gi\|114680497\|ref\|XP_525244.2\| PREDICTED: p47 protein isoform 10 [Pan troglodytes], gi\|114680495\|ref\|...	2.0E-92	[1..339]	[1..370]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAERQEALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS  60
   61 VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [99-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SERSGQQIVG PPRKKSPNEL VDDLFKGAKE HGAVAVERVT KSPGETSKPR VHVVLKLWKS  60
   61 GFSLDNGELR SYQDPSNAQF LESIRRGEVP AELRRLAHGG QVNLDMEDHR DEDFVKPKGA 120
  121 FKAFTGEGQK LGSTAPQVLS TSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.30103
Match:	1ss6A
Description:	Solution structure of SEP domain from human p47
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [242-339]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAQQAENEAK ASSSILIDES EPTTNIQIRL ADGGRLVQKF NHSHRISDIR LFIVDARPAM  60
   61 AATSFILMTT FPNKELADES QTLKEANLLN AVIVQRLT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.522879
Match:	1s3sG
Description:	Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.73741203922834	bayes_pls_golite062009
protein binding	1.6357717410164	bayes_pls_golite062009
small conjugating protein ligase activity	1.16524840930815	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.544811416739	bayes_pls_golite062009
acid-amino acid ligase activity	0.288560953468985	bayes_pls_golite062009
hydrolase activity	0.0740461973842489	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: