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View Structure Prediction Details

Protein: gi|56203342, gi|...
Organism: Homo sapiens
Length: 339 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|56203342, gi|....

Description E-value Query
Range
Subject
Range
gi|109092586 - gi|109092586|ref|XP_001113090.1| PREDICTED: similar to p47 protein isoform b isoform 2 [Macaca mulat...
1.0E-97 [1..339] [1..339]
gi|114680499 - gi|114680499|ref|XP_001153718.1| PREDICTED: p47 protein isoform 1 [Pan troglodytes]
8.0E-96 [1..339] [1..341]
NSF1C_RAT - NSFL1 cofactor p47 OS=Rattus norvegicus GN=Nsfl1c PE=1 SV=1
2.0E-93 [1..339] [1..370]
NSF1C_MOUSE - NSFL1 cofactor p47 OS=Mus musculus GN=Nsfl1c PE=1 SV=1
3.0E-93 [1..339] [1..370]
NSF1C_BOVIN - NSFL1 cofactor p47 OS=Bos taurus GN=NSFL1C PE=2 SV=1
2.0E-92 [1..339] [1..370]
gi|123993027, gi... - gi|124000007|gb|ABM87512.1| NSFL1 (p97) cofactor (p47) [synthetic construct], gi|123993027|gb|ABM841...
NSF1C_PONAB - NSFL1 cofactor p47 OS=Pongo abelii GN=NSFL1C PE=2 SV=1
NSFL1C - NSFL1 (p97) cofactor (p47)
NSF1C_PONPY - NSFL1 cofactor p47 - Pongo pygmaeus (Orangutan)
gi|114680495, gi... - gi|114680497|ref|XP_525244.2| PREDICTED: p47 protein isoform 10 [Pan troglodytes], gi|114680495|ref|...
2.0E-92 [1..339] [1..370]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAERQEALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS  60
   61 VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.560 N/A N/A a.77.1 DEATH domain
View Download 0.536 N/A N/A a.60.12 DNA polymerase beta-like, second domain
View Download 0.527 N/A N/A a.77.1 DEATH domain
View Download 0.493 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.465 N/A N/A a.77.1 DEATH domain

Predicted Domain #2
Region A:
Residues: [99-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SERSGQQIVG PPRKKSPNEL VDDLFKGAKE HGAVAVERVT KSPGETSKPR VHVVLKLWKS  60
   61 GFSLDNGELR SYQDPSNAQF LESIRRGEVP AELRRLAHGG QVNLDMEDHR DEDFVKPKGA 120
  121 FKAFTGEGQK LGSTAPQVLS TSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1ss6A
Description: Solution structure of SEP domain from human p47
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [242-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAQQAENEAK ASSSILIDES EPTTNIQIRL ADGGRLVQKF NHSHRISDIR LFIVDARPAM  60
   61 AATSFILMTT FPNKELADES QTLKEANLLN AVIVQRLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1s3sG
Description: Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.73741203922834 bayes_pls_golite062009
protein binding 1.6357717410164 bayes_pls_golite062009
small conjugating protein ligase activity 1.16524840930815 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.544811416739 bayes_pls_golite062009
acid-amino acid ligase activity 0.288560953468985 bayes_pls_golite062009
hydrolase activity 0.0740461973842489 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle