YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|55957491, gi\|...
Organism:	Homo sapiens
Length:	333 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55957491, gi|....

Description	E-value	Query Range	Subject Range
gi\|48892684, gi\|... - gi\|71675161\|ref\|ZP_00672907.1\| Peptidase S1, chymotrypsin:TPR repeat [Trichodesmium erythraeum IMS10...	3.0E-53	[2..316]	[315..644]
gi\|91204151 - gi\|91204151\|emb\|CAJ71804.1\| conserved hypothetical tpr repeat protein [Candidatus Kuenenia stuttgart...	8.0E-49	[3..326]	[411..758]
gi\|76659271 - gi\|76659271\|ref\|XP_884992.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...	8.0E-49	[3..304]	[81..396]
gi\|56967372, gi\|... - gi\|62821820\|ref\|NP_001017359.1\| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...	1.0E-48	[3..304]	[81..396]
gi\|91079875 - gi\|91079875\|ref\|XP_967579.1\| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]	2.0E-48	[3..304]	[218..533]
SEC_ARATH - Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC OS=Arabidopsis thalian...	3.0E-48	[2..317]	[112..442]
gi\|66793439, gi\|... - gi\|66793439\|ref\|NP_001019747.1\| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Xe...	3.0E-48	[3..304]	[71..386]

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Predicted Domain #1

Region A:
Residues: [1-333]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAAAGTAT SQRFFQSFSD ALIDEDPQAA LEELTKALEQ KPDDAQYYCQ RAYCHILLGN  60
   61 YCVAVADAKK SLELNPNNST AMLRKGICEY HEKNYAAALE TFTEGQKLDS ADANFSVWIK 120
  121 RCQEAQNGSE SEVWTHQSKI KYDWYQTESQ VVITLMIKNV QKNDVNVEFS EKELSALVKL 180
  181 PSGEDYNLKL ELLHPIIPEQ STFKVLSTKI EIKLKKPEAV RWEKLEGQGD VPTPKQFVAD 240
  241 VKNLYPSSSP YTRNWDKLVG EIKEEEKNEK LEGDAALNRL FQQIYSDGSD EVKRAMNKSF 300
  301 MESGGTVLST NWSDVGKRKV EINPPDDMEW KKY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.09691
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	2.40798956799643	bayes_pls_golite062009
small conjugating protein ligase activity	2.35683872990179	bayes_pls_golite062009
binding	2.14253214573541	bayes_pls_golite062009
protein binding	1.65083457326273	bayes_pls_golite062009
acid-amino acid ligase activity	0.907004002487622	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.820063686537832	bayes_pls_golite062009
ligase activity	0.812268484883773	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: