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View Structure Prediction Details

Protein: YKR017C
Organism: Saccharomyces cerevisiae
Length: 551 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR017C.

Description E-value Query
Range
Subject
Range
gi|207343419 - gi|207343419|gb|EDZ70882.1| YKR017Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941561 - gi|151941561|gb|EDN59924.1| conserved protein [Saccharomyces cerevisiae YJM789]
HEL1_YEAST - E3 ubiquitin-protein ligase HEL2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEL1 PE...
gi|190409839 - gi|190409839|gb|EDV13104.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YKR017C - Putative protein of unknown function; contains a RING finger motif
0.0 [1..551] [1..551]
ari-1 - status:Partially_confirmed UniProt:O01965 protein_id:AAB93645.3
0.0 [45..544] [7..487]
gi|3925602 - gi|3925602|emb|CAA10274.1| Ariadne protein (ARI) [Homo sapiens]
0.0 [85..545] [1..456]
gi|166157476 - gi|166157476|ref|NP_001013126.2| ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [...
ARI1_MOUSE - E3 ubiquitin-protein ligase ARIH1 OS=Mus musculus GN=Arih1 PE=1 SV=3
0.0 [83..545] [4..462]
ARI10_ARATH - Probable E3 ubiquitin-protein ligase ARI10 OS=Arabidopsis thaliana GN=ARI10 PE=2 SV=1
0.0 [47..549] [1..495]
FBpp0305074, FBp... - The gene ariadne is referred to in FlyBase by the symbol Dmel\ari-1 (CG5659, FBgn0017418). It is a p...
0.0 [44..541] [1..493]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGTENDQF YSFDESDSSS IELYESHNTS EFTIHGLVFP KLISVTSQDS EFDINEDEDG  60
   61 VDTIYEGMLD APLTKNNKRI LCEGSVPNLS YECLTTKGIF ERMLQRVDHL QPIFAIPSAD 120
  121 ILILLQHYDW NEERLLEVWT EKMDELLVEL GLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TANIKKDNDY NSHFREVEFK NDFTCIICCD KKDTETFALE CGHEYCINCY RHYIKDKLHE  60
   61 GNIITCMDCS LALKNEDIDK VMGHPSSSKL MDSSIKSFVQ KHNRNYKWCP FADCKSIVHL 120
  121 RDTSSLPEYT RLHYSPFVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.045757
Match: 1rmd__
Description: V(D)J recombination activating protein 1 (RAG1), dimerization domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [294-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNSFHRFCFN CGFEVHSPAD CKITTAWVKK ARKESEILNW VLSHTKECPK CSVNIEKNGG  60
   61 CNHMVCSSCK YEFCWICEGP WAPHGKNFFQ CTM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.487 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.384 a.46.1 Methionine synthase domain
View Download 0.353 d.26.3 Chitinase insertion domain
View Download 0.341 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.332 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.302 a.77.1 DEATH domain
View Download 0.299 a.4.5 "Winged helix" DNA-binding domain
View Download 0.262 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.258 a.4.5 "Winged helix" DNA-binding domain
View Download 0.247 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.231 a.163.1 Crustacean CHH/MIH/GIH neurohormone

Predicted Domain #4
Region A:
Residues: [387-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKNNEDNKSK NPQDANKTLK KYTFYYRLFN EHEVSAKLDW NLGQTLGTKV HALQERIGIS  60
   61 WIDGQFLSES LKVLNEGRTV LKWSFAVAYY SDASHNLTKI FVDNQMLLAN AVESLSELLQ 120
  121 IKTPEVIMKR RPEFYNKAGY VENRTTALME CGRELLCKGI CKAAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.07217714843839 bayes_pls_golite062009
binding 2.19426901055464 bayes_pls_golite062009
protein binding 1.62051249360163 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription regulator activity 0.553991532499653 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
DNA binding 0.227671243150662 bayes_pls_golite062009
hydrolase activity 0.156835837705934 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
peptidase activity 0.121357659741468 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [392-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNKSKNPQDA NKTLKKYTFY YRLFNEHEVS AKLDWNLGQT LGTKVHALQE RIGISWIDGQ  60
   61 FLSESLKVLN EGRTVLKWSF AVAYYSDASH NLTKIFVDNQ MLLANAVESL SELLQIKTPE 120
  121 VIMKRRPEFY NKAGYVENRT TALMECGREL LCKGICKAAE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle