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View Structure Prediction Details

Protein: TOR1
Organism: Saccharomyces cerevisiae
Length: 2470 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOR1.

Description E-value Query
Range
Subject
Range
TOR2 - PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth i...
TOR2_YEAST - Serine/threonine-protein kinase TOR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOR...
0.0 [37..2470] [42..2474]
MTOR_RAT - Serine/threonine-protein kinase mTOR OS=Rattus norvegicus GN=Mtor PE=1 SV=1
0.0 [72..2470] [20..2549]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [78..2470] [4..2337]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [37..2470] [42..2474]
MTOR - mechanistic target of rapamycin (serine/threonine kinase)
0.0 [72..2470] [20..2549]
TOR_ARATH - Serine/threonine-protein kinase TOR OS=Arabidopsis thaliana GN=TOR PE=1 SV=1
0.0 [54..2470] [22..2481]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPHEEQIWK SKLLKAANND MDMDRNVPLA PNLNVNMNMK MNASRNGDEF GLTSSRFDGV  60
   61 VIGSNGDVNF KPILEKIFRE LTSDY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.738 d.50.1 dsRNA-binding domain-like
View Download 0.672 a.3.1 Cytochrome c
View Download 0.529 a.3.1 Cytochrome c
View Download 0.485 a.135.1 Tetraspanin
View Download 0.474 a.39.1 EF-hand
View Download 0.430 d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.423 a.3.1 Cytochrome c
View Download 0.410 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.363 a.24.15 FAD-dependent thiol oxidase
View Download 0.342 a.156.1 S13-like H2TH domain
View Download 0.341 d.95.2 Homing endonucleases
View Download 0.337 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.333 a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.323 a.112.1 Description not found.
View Download 0.316 b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.314 a.3.1 Cytochrome c
View Download 0.311 d.129.1 TATA-box binding protein-like
View Download 0.311 d.141.1 Ribosomal protein L6
View Download 0.293 c.98.1 MurE/MurF N-terminal domain
View Download 0.278 a.4.5 "Winged helix" DNA-binding domain
View Download 0.273 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.271 c.47.1 Thioredoxin-like
View Download 0.255 a.24.17 Group V grass pollen allergen
View Download 0.240 d.93.1 SH2 domain
View Download 0.239 b.38.1 Sm-like ribonucleoproteins
View Download 0.229 a.24.17 Group V grass pollen allergen
View Download 0.227 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.226 b.55.1 PH domain-like
View Download 0.225 d.56.1 GroEL-intermediate domain like
View Download 0.216 a.74.1 Cyclin-like
View Download 0.209 d.201.1 SRP19
View Download 0.203 c.57.1 Molybdenum cofactor biosynthesis proteins

Predicted Domain #2
Region A:
Residues: [86-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEERKLASIS LFDLLVSLEH ELSIEEFQAV SNDINNKILE LVHTKKTSTR VGAVLSIDTL  60
   61 ISFYAYTERL PNETSRLAGY LRGLIPSNDV EVMRLAAKTL GKLAVPGGTY TSDFVEFEIK 120
  121 SCLEWLTAST EKNSFSSSKP DHAKHAALLI ITALAENCPY LLYQYLNSIL DNIWRALRDP 180
  181 HLVIRIDASI TLAKCLSTLR NRDPQLTSQW VQRLATSCEY GFQVNTLECI HASLLVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.221849
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein transporter activity 3.92743254165888 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
clathrin binding 3.06608550312523 bayes_pls_golite062009
protein binding 2.78733902345842 bayes_pls_golite062009
transporter activity 2.48700774379895 bayes_pls_golite062009
nucleic acid binding 2.33018407596597 bayes_pls_golite062009
substrate-specific transporter activity 2.26725422172281 bayes_pls_golite062009
transcription regulator activity 2.16673352512615 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.81975432004022 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.77299972560401 bayes_pls_golite062009
DNA binding 1.7075005295555 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.62227684952907 bayes_pls_golite062009
kinase activity 1.60994283310715 bayes_pls_golite062009
hydrolase activity 1.50413178466141 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.50380925936701 bayes_pls_golite062009
protein kinase activity 1.39674032951965 bayes_pls_golite062009
transmembrane transporter activity 1.28481004323799 bayes_pls_golite062009
transferase activity 1.25186057612742 bayes_pls_golite062009
cell adhesion molecule binding 1.10202633941671 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.09652988954158 bayes_pls_golite062009
molecular transducer activity 1.05960420053443 bayes_pls_golite062009
signal transducer activity 1.05960420053443 bayes_pls_golite062009
transcription factor activity 1.00193525671783 bayes_pls_golite062009
cytoskeletal protein binding 0.773975545005505 bayes_pls_golite062009
protein transmembrane transporter activity 0.77052454980864 bayes_pls_golite062009
enzyme regulator activity 0.698613639309592 bayes_pls_golite062009
protein phosphatase binding 0.67117954368313 bayes_pls_golite062009
protein serine/threonine kinase activity 0.638990331710836 bayes_pls_golite062009
actin binding 0.572473732371314 bayes_pls_golite062009
phosphatase binding 0.5597863594782 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
structure-specific DNA binding 0.331309559699391 bayes_pls_golite062009
active transmembrane transporter activity 0.252495966234234 bayes_pls_golite062009
ion transmembrane transporter activity 0.248585912061178 bayes_pls_golite062009
primary active transmembrane transporter activity 0.226380819487924 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.217517113570989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.178770060806735 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.175241020572885 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.174922130116569 bayes_pls_golite062009
transcription activator activity 0.160275383613705 bayes_pls_golite062009
cadherin binding 0.1400783779596 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.100181463251306 bayes_pls_golite062009
nuclear localization sequence binding 0.0935103343162811 bayes_pls_golite062009
pyrophosphatase activity 0.0635404099346928 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0548082069333885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.052195223119721 bayes_pls_golite062009
kinase binding 0.046676627148301 bayes_pls_golite062009
cation transmembrane transporter activity 0.0405268469927988 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.0332743336452223 bayes_pls_golite062009
GTPase regulator activity 0.0268373969988844 bayes_pls_golite062009
transcription factor binding 0.0221966060394205 bayes_pls_golite062009
guanyl ribonucleotide binding 0.00234756529236324 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [323-503]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEILFLKDPF LNQVFDQMCL NCIAYENHKA KMIREKIYQI VPLLASFNPQ LFAGKYLHQI  60
   61 MDNYLEILTN APANKIPHLK DDKPQILISI GDIAYEVGPD IAPYVKQILD YIEHDLQTKF 120
  121 KFRKKFENEI FYCIGRLAVP LGPVLGKLLN RNILDLMFKC PLSDYMQETF QILTERIPSL 180
  181 G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.221849
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [504-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKINDELLNL VCSTLSGTPF IQPGSPMEIP SFSRERAREW RNKNILQKTG ESNDDNNDIK  60
   61 IIIQAFRMLK NIKSRFSLVE FVRIVALSYI EHTDPRVRKL AALTSCEIYV KDNICKQTSL 120
  121 HS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.221849
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [626-760]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNTVSEVLSK LLAITIADPL QDIRLEVLKN LNPCFDPQLA QPDNLRLLFT ALHDESFNIQ  60
   61 SVAMELVGRL SSVNPAYVIP SIRKILLELL TKLKFSTSSR EKEETASLLC TLIRSSKDVA 120
  121 KPYIEPLLNV LLPKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.221849
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [761-988]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDTSSTVAST ALRTIGELSV VGGEDMKIYL KDLFPLIIKT FQDQSNSFKR EAALKALGQL  60
   61 AASSGYVIDP LLDYPELLGI LVNILKTENS QNIRRQTVTL IGILGAIDPY RQKEREVTST 120
  121 TDISTEQNAP PIDIALLMQG MSPSNDEYYT TVVIHCLLKI LKDPSLSSYH TAVIQAIMHI 180
  181 FQTLGLKCVS FLDQIIPTIL DVMRTCSQSL LEFYFQQLCS LIIIVRQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.221849
Match: 1qgkA_
Description: Importin beta
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [989-1226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRPHVDSIFQ AIKDFSSVAK LQITLVSVIE AISKALEGEF KRLVPLTLTL FLVILENDKS  60
   61 SDKVLSRRVL RLLESFGPNL EGYSHLITPK IVQMAEFTSG NLQRSAIITI GKLAKDVDLF 120
  121 EMSSRIVHSL LRVLSSTTSD ELSKVIMNTL SLLLIQMGTS FAIFIPVINE VLMKKHIQHT 180
  181 IYDDLTNRIL NNDVLPTKIL EANTTDYKPA EQMEAADAGV AKLPINQSVL KSAWNSSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.154902
Match: 1b3uA_
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
1-phosphatidylinositol-3-kinase activity 6.25653789181171 bayes_pls_golite062009
phosphoinositide 3-kinase activity 6.23876192310792 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
neurexin binding 4.1106220854373 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
lipid kinase activity 3.32869674544617 bayes_pls_golite062009
inositol or phosphatidylinositol kinase activity 3.07779388034304 bayes_pls_golite062009
clathrin binding 3.06608550312523 bayes_pls_golite062009
insulin receptor activity 2.91728725389216 bayes_pls_golite062009
protein tyrosine kinase activity 2.8153155526437 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
PTB domain binding 2.68841114010895 bayes_pls_golite062009
molecular transducer activity 2.40586892801446 bayes_pls_golite062009
signal transducer activity 2.40586892801446 bayes_pls_golite062009
protein binding 2.276111749106 bayes_pls_golite062009
receptor signaling protein activity 2.10379226653669 bayes_pls_golite062009
GTPase activity 2.07905155389729 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
calcium-dependent phospholipid binding 1.85892769686753 bayes_pls_golite062009
phosphoinositide 3-kinase binding 1.82515074380651 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.81975432004022 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.81249386965144 bayes_pls_golite062009
transmembrane receptor protein kinase activity 1.7769021678395 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.77299972560401 bayes_pls_golite062009
transmembrane receptor activity 1.6878868450299 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
insulin receptor substrate binding 1.59061960750503 bayes_pls_golite062009
receptor activity 1.57112777506542 bayes_pls_golite062009
transcription regulator activity 1.56748951434625 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 1.4571078357189 bayes_pls_golite062009
peptidase activity 1.4194137915074 bayes_pls_golite062009
kinase binding 1.26086833316556 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transporter activity 1.11833481501707 bayes_pls_golite062009
DNA binding 1.10840413397037 bayes_pls_golite062009
protein kinase binding 1.06030596516506 bayes_pls_golite062009
nucleic acid binding 1.04820278247375 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.02752755983942 bayes_pls_golite062009
transmembrane transporter activity 0.97575992765505 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.959360414036299 bayes_pls_golite062009
hydrolase activity 0.950393847838778 bayes_pls_golite062009
transcription factor activity 0.904613968623246 bayes_pls_golite062009
protein complex binding 0.810706883199821 bayes_pls_golite062009
protein transmembrane transporter activity 0.77052454980864 bayes_pls_golite062009
3-phosphoinositide-dependent protein kinase binding 0.766462410372719 bayes_pls_golite062009
substrate-specific transporter activity 0.705905455086486 bayes_pls_golite062009
stem cell factor receptor activity 0.702866451999818 bayes_pls_golite062009
transcription repressor activity 0.568332175782799 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.51726292539973 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
enzyme binding 0.46284745266176 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.450699332958421 bayes_pls_golite062009
protein kinase C activity 0.41587987561486 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
insulin receptor binding 0.379040209226037 bayes_pls_golite062009
SNARE binding 0.3731056408292 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
protein transporter activity 0.322729515821394 bayes_pls_golite062009
cytoskeletal protein binding 0.284465446035567 bayes_pls_golite062009
structure-specific DNA binding 0.267404531445803 bayes_pls_golite062009
transforming growth factor beta receptor activity 0.26602283402868 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase activity 0.26602283402868 bayes_pls_golite062009
active transmembrane transporter activity 0.252495966234234 bayes_pls_golite062009
primary active transmembrane transporter activity 0.226380819487924 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.217517113570989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.178770060806735 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.175241020572885 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.174922130116569 bayes_pls_golite062009
ion transmembrane transporter activity 0.148194101970458 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate 3-kinase activity 0.147483323744488 bayes_pls_golite062009
actin binding 0.144822861207099 bayes_pls_golite062009
nuclear localization sequence binding 0.0935103343162811 bayes_pls_golite062009
MAP kinase activity 0.08504542461349 bayes_pls_golite062009
growth factor binding 0.0526340287295695 bayes_pls_golite062009
transforming growth factor beta receptor activity, type I 0.0506751594607393 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0040394359628233 bayes_pls_golite062009
SH2 domain binding 2.96656737540424E-4 bayes_pls_golite062009

Predicted Domain #8
Region A:
Residues: [1227-1323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRTKEDWQEW SKRLSIQLLK ESPSHALRAC SNLASMYYPL AKELFNTAFA CVWTELYSQY  60
   61 QEDLIGSLCI ALSSPLNPPE IHQTLLNLVE FMEHDDK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.817 0.002 endosome membrane a.118.1 ARM repeat
View Download 0.769 0.002 endosome membrane a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.824 0.002 endosome membrane a.118.9 ENTH/VHS domain
View Download 0.767 0.002 endosome membrane a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.907 0.002 endosome membrane a.118.11 Cytochrome c oxidase subunit E
View Download 0.722 0.002 endosome membrane a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.699 0.002 endosome membrane a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.693 0.002 endosome membrane a.118.9 ENTH/VHS domain
View Download 0.634 0.002 endosome membrane a.24.17 Group V grass pollen allergen
View Download 0.628 0.002 endosome membrane a.61.1 Retroviral matrix proteins
View Download 0.618 0.002 endosome membrane a.85.1 Hemocyanin, N-terminal domain
View Download 0.600 0.002 endosome membrane a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.566 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.566 0.002 endosome membrane a.95.1 Influenza virus matrix protein M1
View Download 0.544 0.002 endosome membrane c.55.4 Translational machinery components
View Download 0.538 0.002 endosome membrane a.118.8 TPR-like
View Download 0.521 0.002 endosome membrane a.74.1 Cyclin-like
View Download 0.518 0.002 endosome membrane d.8.1 Urease, gamma-subunit
View Download 0.513 0.002 endosome membrane a.7.5 Tubulin chaperone cofactor A
View Download 0.500 0.002 endosome membrane a.40.1 Calponin-homology domain, CH-domain
View Download 0.489 0.002 endosome membrane a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.487 0.002 endosome membrane a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.485 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.479 0.002 endosome membrane a.39.1 EF-hand
View Download 0.475 0.002 endosome membrane a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.475 0.002 endosome membrane a.118.8 TPR-like
View Download 0.472 0.002 endosome membrane d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.449 0.002 endosome membrane a.61.1 Retroviral matrix proteins
View Download 0.439 0.002 endosome membrane a.81.1 N-terminal domain of DnaB helicase
View Download 0.433 0.002 endosome membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.432 0.002 endosome membrane a.1.1 Globin-like
View Download 0.430 0.002 endosome membrane d.141.1 Ribosomal protein L6
View Download 0.425 0.002 endosome membrane a.49.1 C-terminal domain of B transposition protein
View Download 0.421 0.002 endosome membrane a.131.1 Peridinin-chlorophyll protein
View Download 0.417 0.002 endosome membrane a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.414 0.002 endosome membrane c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.407 0.002 endosome membrane a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.400 0.002 endosome membrane d.52.7 Ribosome-binding factor A, RbfA
View Download 0.393 0.002 endosome membrane a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.390 0.002 endosome membrane a.65.1 Annexin
View Download 0.387 0.002 endosome membrane a.11.2 Second domain of FERM
View Download 0.383 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.383 0.002 endosome membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.375 0.002 endosome membrane b.34.8 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
View Download 0.375 0.002 endosome membrane a.77.1 DEATH domain
View Download 0.372 0.002 endosome membrane a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.362 0.002 endosome membrane a.77.1 DEATH domain
View Download 0.359 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.347 0.002 endosome membrane a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.347 0.002 endosome membrane a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.341 0.002 endosome membrane a.85.1 Hemocyanin, N-terminal domain
View Download 0.340 0.002 endosome membrane a.46.1 Methionine synthase domain
View Download 0.339 0.002 endosome membrane a.7.6 Ribosomal protein S20
View Download 0.338 0.002 endosome membrane a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.337 0.002 endosome membrane a.118.8 TPR-like
View Download 0.337 0.002 endosome membrane a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.335 0.002 endosome membrane f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.335 0.002 endosome membrane a.158.1 F-box domain
View Download 0.334 0.002 endosome membrane a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.326 0.002 endosome membrane a.5.4 Elongation factor TFIIS domain 2
View Download 0.321 0.002 endosome membrane d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.315 0.002 endosome membrane d.58.49 YajQ-like
View Download 0.313 0.002 endosome membrane a.11.1 Acyl-CoA binding protein
View Download 0.306 0.002 endosome membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.302 0.002 endosome membrane a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.301 0.002 endosome membrane a.1.1 Globin-like
View Download 0.298 0.002 endosome membrane a.157.1 Skp1 dimerisation domain-like
View Download 0.293 0.002 endosome membrane a.4.12 TrpR-like
View Download 0.288 0.002 endosome membrane a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.287 0.002 endosome membrane d.80.1 Tautomerase/MIF
View Download 0.286 0.002 endosome membrane a.61.1 Retroviral matrix proteins
View Download 0.283 0.002 endosome membrane a.29.4 RecG, N-terminal domain
View Download 0.280 0.002 endosome membrane a.39.1 EF-hand
View Download 0.276 0.002 endosome membrane a.77.1 DEATH domain
View Download 0.275 0.002 endosome membrane a.60.9 lambda integrase-like, N-terminal domain
View Download 0.275 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.274 0.002 endosome membrane d.224.1 SufE-like
View Download 0.273 0.002 endosome membrane a.51.1 Cytochrome c oxidase subunit h
View Download 0.271 0.002 endosome membrane a.142.1 PTS-regulatory domain, PRD
View Download 0.270 0.002 endosome membrane a.118.1 ARM repeat
View Download 0.268 0.002 endosome membrane a.118.8 TPR-like
View Download 0.268 0.002 endosome membrane d.52.4 YhbC-like, N-terminal domain
View Download 0.266 0.002 endosome membrane a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.264 0.002 endosome membrane a.118.1 ARM repeat
View Download 0.264 0.002 endosome membrane a.118.14 FliG
View Download 0.263 0.002 endosome membrane d.58.14 Ribosomal protein S6
View Download 0.258 0.002 endosome membrane a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.257 0.002 endosome membrane a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.256 0.002 endosome membrane a.1.1 Globin-like
View Download 0.254 0.002 endosome membrane d.58.5 GlnB-like
View Download 0.249 0.002 endosome membrane a.61.1 Retroviral matrix proteins
View Download 0.247 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.243 0.002 endosome membrane a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.237 0.002 endosome membrane a.64.1 Saposin
View Download 0.236 0.002 endosome membrane a.17.1 p8-MTCP1
View Download 0.236 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.235 0.002 endosome membrane a.118.1 ARM repeat
View Download 0.230 0.002 endosome membrane f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.229 0.002 endosome membrane d.41.2 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
View Download 0.229 0.002 endosome membrane a.3.1 Cytochrome c
View Download 0.228 0.002 endosome membrane a.74.1 Cyclin-like
View Download 0.226 0.002 endosome membrane a.4.5 "Winged helix" DNA-binding domain
View Download 0.224 0.002 endosome membrane a.118.1 ARM repeat
View Download 0.223 0.002 endosome membrane a.29.2 Bromodomain
View Download 0.222 0.002 endosome membrane a.77.1 DEATH domain
View Download 0.220 0.002 endosome membrane d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.216 0.002 endosome membrane a.26.1 4-helical cytokines
View Download 0.216 0.002 endosome membrane a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.214 0.002 endosome membrane a.47.2 t-snare proteins
View Download 0.212 0.002 endosome membrane a.59.1 PAH2 domain
View Download 0.211 0.002 endosome membrane c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.208 0.002 endosome membrane d.94.1 HPr-like
View Download 0.207 0.002 endosome membrane a.138.1 Multiheme cytochromes
View Download 0.207 0.002 endosome membrane a.29.2 Bromodomain
View Download 0.204 0.002 endosome membrane a.60.1 SAM/Pointed domain
View Download 0.202 0.002 endosome membrane a.24.15 FAD-dependent thiol oxidase
View Download 0.201 0.002 endosome membrane a.2.3 Chaperone J-domain

Predicted Domain #9
Region A:
Residues: [1324-1919]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALPIPTQSLG EYAERCHAYA KALHYKEIKF IKEPENSTIE SLISINNQLN QTDAAIGILK  60
   61 HAQQHHSLQL KETWFEKLER WEDALHAYNE REKAGDTSVS VTLGKMRSLH ALGEWEQLSQ 120
  121 LAARKWKVSK LQTKKLIAPL AAGAAWGLGE WDMLEQYISV MKPKSPDKEF FDAILYLHKN 180
  181 DYDNASKHIL NARDLLVTEI SALINESYNR AYSVIVRTQI ITEFEEIIKY KQLPPNSEKK 240
  241 LHYQNLWTKR LLGCQKNVDL WQRVLRVRSL VIKPKQDLQI WIKFANLCRK SGRMRLANKA 300
  301 LNMLLEGGND PSLPNTFKAP PPVVYAQLKY IWATGAYKEA LNHLIGFTSR LAHDLGLDPN 360
  361 NMIAQSVKLS SASTAPYVEE YTKLLARCFL KQGEWRIATQ PNWRNTNPDA ILGSYLLATH 420
  421 FDKNWYKAWH NWALANFEVI SMVQEETKLN GGKNDDDDDT AVNNDNVRID GSILGSGSLT 480
  481 INGNRYPLEL IQRHVVPAIK GFFHSISLLE TSCLQDTLRL LTLLFNFGGI KEVSQAMYEG 540
  541 FNLMKIENWL EVLPQLISRI HQPDPTVSNS LLSLLSDLGK AHPQALVYPL TVAIKS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 235.376751
Match: PF02259
Description: FAT domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1920-2084]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESVSRQKAAL SIIEKIRIHS PVLVNQAELV SHELIRVAVL WHELWYEGLE DASRQFFVEH  60
   61 NIEKMFSTLE PLHKHLGNEP QTLSEVSFQK SFGRDLNDAY EWLNNYKKSK DINNLNQAWD 120
  121 IYYNVFRKIT RQIPQLQTLD LQHVSPQLLA THDLELAVPG TYFPG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 332.30103
Match: 1aueA_
Description: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
Matching Structure (courtesy of the PDB):

Predicted Domain #11
Region A:
Residues: [2085-2436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPTIRIAKFE PLFSVISSKQ RPRKFSIKGS DGKDYKYVLK GHEDIRQDSL VMQLFGLVNT  60
   61 LLKNDSECFK RHLDIQQYPA IPLSPKSGLL GWVPNSDTFH VLIREHRDAK KIPLNIEHWV 120
  121 MLQMAPDYEN LTLLQKIEVF TYALDNTKGQ DLYKILWLKS RSSETWLERR TTYTRSLAVM 180
  181 SMTGYILGLG DRHPSNLMLD RITGKVIHID FGDCFEAAIL REKYPEKVPF RLTRMLTYAM 240
  241 EVSGIEGSFR ITCENVMRVL RDNKESLMAI LEAFALDPLI HWGFDLPPQK LTEQTGIPLP 300
  301 LINPSELLRK GAITVEEAAN MEAEQQNETK NARAMLVLRR ITDKLTGNDI KR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 123.60206
Match: PF00454
Description: Phosphatidylinositol 3- and 4-kinase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [2437-2470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNELDVPEQV DKLIQQATSI ERLCQHYIGW CPFW

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 17.130768
Match: PF02260
Description: FATC domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle