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View Structure Prediction Details

Protein: RAD26
Organism: Saccharomyces cerevisiae
Length: 1085 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD26.

Description E-value Query
Range
Subject
Range
gi|550429 - gi|550429|emb|CAA57290.1| RAD26 [Saccharomyces cerevisiae]
0.0 [1..1085] [1..1085]
SMARCA4 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
0.0 [4..1083] [448..1523]
gi|996018, gi|45... - gi|996018|emb|CAA62831.1| BRG1 protein [Gallus gallus], gi|45384232|ref|NP_990390.1| BRG1 protein [G...
0.0 [4..1083] [446..1507]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..1083] [447..1489]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [4..1083] [447..1489]

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Predicted Domain #1
Region A:
Residues: [1-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKEQQDNA KLENNESLKD LGVNVLSQSS LEEKIANDVT NFSNLQSLQQ EETRLERSKT  60
   61 ALQRYVNKKN HLTRKLNNTT RISVKQNLRD QIKNLQSDDI ERVLKDIDDI QSRIKELKEQ 120
  121 VDQGAENKGS KEGLQRPGET EKEFLIRTGK ITAFGHKAGF SLDTANREYA KNDEQKDEDF 180
  181 EMATEQMVEN LTDEDDNLSD QDYQMSGKES EDDEEEENDD KILKELEDLR FRGQPGEAKD 240
  241 DGDELYYQER LKKWVKQRSC GSQRSSDLPE WRRPHPNIPD AKLNS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [286-600]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFKIPGEIYS LLFNYQKTCV QWLYELYQQN CGGIIGDEMG LGKTIQVIAF IAALHHSGLL  60
   61 TGPVLIVCPA TVMKQWCNEF QHWWPPLRTV ILHSMGSGMA SDQKFKMDEN DLENLIMNSK 120
  121 PSDFSYEDWK NSTRTKKALE SSYHLDKLID KVVTDGHILI TTYVGLRIHS DKLLKVKWQY 180
  181 AVLDEGHKIR NPDSEISLTC KKLKTHNRII LSGTPIQNNL TELWSLFDFI FPGKLGTLPV 240
  241 FQQQFVIPIN IGGYANATNI QVQTGYKCAV ALRDLISPYL LRRVKADVAK DLPQKKEMVL 300
  301 FCKLTKYQRS KYLEF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 112.79588
Match: PF00176
Description: SNF2 family N-terminal domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.2394894333307 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
chromatin binding 2.9265077396229 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
transcription repressor activity 2.35473783647299 bayes_pls_golite062009
nucleic acid binding 1.7870619298179 bayes_pls_golite062009
DNA binding 1.72304410722296 bayes_pls_golite062009
histone binding 1.48525673080866 bayes_pls_golite062009
transcription activator activity 1.1132810573451 bayes_pls_golite062009
methylated histone residue binding 0.32228411301259 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [601-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHSSDLNQIQ NGKRNVLFGI DILRKICNHP DLLDRDTKRH NPDYGDPKRS GKMQVVKQLL  60
   61 LLWHKQGYKA LLFTQSRQML DILEEFISTK DPDLSHLNYL RMDGTTNIKG RQSLVDRFNN 120
  121 ESFDVFLLTT RVGGLGVNLT GANRIIIFDP DWNPSTDMQA RERAWRIGQK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.02893949194171 bayes_pls_golite062009
pyrophosphatase activity 1.97909493766908 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.95844964816653 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.95658009428828 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
ATPase activity 1.42257610975945 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
helicase activity 1.16085745407703 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
hydrolase activity 0.98565595572967 bayes_pls_golite062009
ATPase activity, coupled 0.732723553251109 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
structure-specific DNA binding 0.720649395550746 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
ATP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
double-stranded DNA binding 0.58862275163252 bayes_pls_golite062009
transcription activator activity 0.537911793669378 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
structural constituent of ribosome 0.396187998943318 bayes_pls_golite062009
microtubule motor activity 0.38363601832205 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.22150712609541 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
substrate-specific transporter activity 0.144154288308693 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
motor activity 0.0492172159259601 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [771-958]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REVSIYRLMV GGSIEEKIYH RQIFKQFLTN RILTDPKQKR FFKIHELHDL FSLGGENGYS  60
   61 TEELNEEVQK HTENLKNSKS EESDDFEQLV NLSGVSKLES FYNGKEKKEN SKTEDDRLIE 120
  121 GLLGGESNLE TVMSHDSVVN SHAGSSSSNI ITKEASRVAI EAVNALRKSR KKITKQYEIG 180
  181 TPTWTGRF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [959-1085]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKAGKIRKRD PLKNKLTGSA AILGNITKSQ KEASKEARQE NYDDGITFAR SKEINSNTKT  60
   61 LENIRAYLQK QNNFFSSSVS ILNSIGVSLS DKEDVIKVRA LLKTIAQFDK ERKGWVLDEE 120
  121 FRNNNAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle