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View Structure Prediction Details

Protein: STN1
Organism: Saccharomyces cerevisiae
Length: 494 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STN1.

Description E-value Query
Range
Subject
Range
STN1 - Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action ...
STN1_YEAST - Protein STN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STN1 PE=1 SV=1
0.0 [1..494] [1..494]

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Predicted Domain #1
Region A:
Residues: [1-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKYGHIAHQ EGDVCYYIPR LFKYNSYYSG TEDVRIFVGD LKYRMRVSLQ ICEKYYDRRL  60
   61 SMLFWKNHPL QQIHLIGCII GLQFKWIGKQ EYIFFQLDDC TSDSSLVGYT SDMRFLTCKV 120
  121 KKDSILSWGL NITDLIGLTL HVYGQASLNY QELQVEYLRL CYSLTEEIDH WKITMNMREQ 180
  181 LDTPWSLSDF VIGELFTQEQ EWTPETSQIE VVNPDFVGIG YKTPESKRNE TTFIEQLQEE 240
  241 RLKDELEIIS PYNSTDTSNS VHSLSFRFVS SLKDFPETHF LNSGDQIDNG NDEQLKKLEY 300
  301 QSANLPVMIP NRTSAKSNLM LILLGLQMKE ISNSDLYKLK EVRSVVTSLA SFLFQQQNVG 360
  361 VMKSFDSLEK EAFRDLVNRL VSQGLIGLKD KTSETFDLLP LKNLFEYAEK RISVLMKLQC 420
  421 YTGTVQLSHV QEKLHLPYIT TNGIVDVFKE CLKRTKKQYP EVLKNWWIDL DPKNGMEDQN 480
  481 SGILLHLEYA AAYS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
telomerase inhibitor activity 7.4045795951838 bayes_pls_golite062009
telomeric DNA binding 6.80354805962079 bayes_pls_golite062009
single-stranded telomeric DNA binding 6.768584842828 bayes_pls_golite062009
nucleic acid binding 3.7851057288689 bayes_pls_golite062009
DNA binding 3.36845392994723 bayes_pls_golite062009
DEAD/H-box RNA helicase binding 3.18920599157105 bayes_pls_golite062009
binding 2.75191943661749 bayes_pls_golite062009
structure-specific DNA binding 2.74795067107907 bayes_pls_golite062009
single-stranded DNA binding 2.64392934015868 bayes_pls_golite062009
structural constituent of ribosome 1.93610624899943 bayes_pls_golite062009
transcription regulator activity 1.87401014198878 bayes_pls_golite062009
structural molecule activity 1.75354740531381 bayes_pls_golite062009
transcription repressor activity 1.11970004248085 bayes_pls_golite062009
DNA helicase activity 1.03434608237928 bayes_pls_golite062009
transcription factor activity 0.967319786833633 bayes_pls_golite062009
sequence-specific DNA binding 0.753061173202428 bayes_pls_golite062009
DNA-dependent ATPase activity 0.633347054314125 bayes_pls_golite062009
nucleotidyltransferase activity 0.451086694866543 bayes_pls_golite062009
nuclease activity 0.344602655860014 bayes_pls_golite062009
ribonuclease activity 0.327087435405429 bayes_pls_golite062009
translation regulator activity 0.272395932340767 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.224702431869342 bayes_pls_golite062009
protein binding 0.185497104009134 bayes_pls_golite062009
exonuclease activity 0.123437412322173 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [311-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRTSAKSNLM LILLGLQMKE ISNSDLYKLK EVRSVVTSLA SFLFQQQNVG VMKSFDSLEK  60
   61 EAFRDLVNRL VSQGLIGLKD KTSETFDLLP LKNLFEYAEK RISVLMKLQC YTGTVQLSHV 120
  121 QEKLHLPYIT TNGIVDVFKE CLKRTKKQYP EVLKNWWIDL DPKNGMEDQN SGILLHLEYA 180
  181 AAYS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle