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View Structure Prediction Details

Protein: ATG8
Organism: Saccharomyces cerevisiae
Length: 117 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG8.

Description E-value Query
Range
Subject
Range
gi|2072023 - gi|2072023|gb|AAB53650.1| symbiosis-related protein [Laccaria bicolor]
6.0E-51 [1..117] [12..128]
gi|2465192 - gi|2465192|gb|AAB72082.1| polyprotein [pestivirus type 1]
1.0E-48 [1..116] [598..715]
ATG8A_ARATH - Autophagy-related protein 8a OS=Arabidopsis thaliana GN=ATG8A PE=1 SV=2
3.0E-48 [2..116] [3..117]
ATG8_NEUCR - Autophagy-related protein 8 OS=Neurospora crassa GN=atg-8 PE=3 SV=1
ATG8_NEUCR - Autophagy-related protein 8 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM ...
7.0E-47 [1..116] [1..116]
ATG8_SCHPO - Autophagy-related protein 8 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg8 PE=3 SV=1
atg8 - autophagy associated protein Atg8
4.0E-46 [1..116] [1..116]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSTFKSEYP FEKRKAESER IADRFKNRIP VICEKAEKSD IPEIDKRKYL VPADLTVGQF  60
   61 VYVIRKRIML PPEKAIFIFV NDTLPPTAAL MSAIYQEHKD KDGFLYVTYS GENTFGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 366.69897
Match: 1eo6A_
Description: Golgi-associated ATPase enhancer of 16 kD, Gate-16
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
tubulin binding 3.8719684227967 bayes_pls_golite062009
small conjugating protein ligase activity 3.71144418714309 bayes_pls_golite062009
microtubule binding 3.61517229466799 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.30801071565148 bayes_pls_golite062009
cytoskeletal protein binding 3.11253399564789 bayes_pls_golite062009
beta-tubulin binding 2.878827078106 bayes_pls_golite062009
binding 2.786655943372 bayes_pls_golite062009
acid-amino acid ligase activity 2.72499875710239 bayes_pls_golite062009
GABA receptor binding 2.41579236188889 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
transcription regulator activity 1.42747465816672 bayes_pls_golite062009
nucleic acid binding 1.32707653701567 bayes_pls_golite062009
DNA binding 1.22622447288034 bayes_pls_golite062009
molecular transducer activity 0.87452559909702 bayes_pls_golite062009
signal transducer activity 0.87452559909702 bayes_pls_golite062009
SUMO ligase activity 0.80391127659342 bayes_pls_golite062009
hydrolase activity 0.79940718386175 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.753885975469065 bayes_pls_golite062009
structural constituent of ribosome 0.599634454232833 bayes_pls_golite062009
structural molecule activity 0.576819726104993 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
protein kinase activity 0.325253662829604 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
transferase activity 0.236208643697075 bayes_pls_golite062009

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