YRC Public Data Repository - Protein Structure Prediction

Protein:	CG7220-PE, CG722...
Organism:	Drosophila melanogaster
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7220-PE, CG722....

Description	E-value	Query Range	Subject Range
gi\|62738886 - gi\|62738886\|pdb\|1Z2U\|A Chain A, The 1.1a Crystallographic Structure Of Ubiquitin- Conjugating Enzyme...	186.0	[0..40]	[189..2]
gi\|109066782 - gi\|109066782\|ref\|XP_001096263.1\| PREDICTED: similar to ubiquitin-conjugating enzyme E2D 4 (putative)... gi\|114613001, gi... - gi\|114613001\|ref\|XP_519070.2\| PREDICTED: ubiquitin-conjugating enzyme E2D 4 (putative) isoform 4 [Pa... UBE2D4 - ubiquitin-conjugating enzyme E2D 4 (putative)	185.0	[0..43]	[189..2]
gi\|37590333, gi\|... - gi\|41152425\|ref\|NP_955958.1\| ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) [Danio rerio...	185.0	[0..43]	[189..2]
gi\|109509992 - gi\|109509992\|ref\|XP_001080152.1\| PREDICTED: similar to ubiquitin-conjugating enzyme E2D 1, UBC4/5 ho...	185.0	[0..3]	[189..193]
gi\|116487484, gi... - gi\|118404876\|ref\|NP_001072891.1\| ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog) [Xenopus (Silur... gi\|54311502, gi\|... - gi\|54311502\|gb\|AAH84849.1\| LOC495381 protein [Xenopus laevis], gi\|49899030\|gb\|AAH76728.1\| Ube2d2-pro...	184.0	[0..43]	[189..2]
gi\|48095652, gi\|... - ref\|XP_392337.1\| similar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiqu...	184.0	[0..43]	[189..2]
gi\|87239726 - gi\|87239726\|emb\|CAJ57642.1\| putative ubiquitin conjugating enzyme 2 [Oesophagostomum dentatum]	184.0	[0..43]	[189..2]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKLFKKPKD KIPKSEILTE PKEPKTPPVS KCGKPLQLDN SRWERRLHKE LMSLIKEPPP  60
   61 GVTIDTESVQ QNLSEWKINI KGFEGTLYEG EDFQLLFKFN NKYPFDSPEV TFIGTNIPVH 120
  121 PHVYSNGHIC LSILTEDWSP ALSVQSVCLS IASMLSSCRE KKRPPDNTIY VKTCNKNPKK 180
  181 TKWWYHDDSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.39794
Match:	2a7lA
Description:	Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
small conjugating protein ligase activity	6.80727357703118	bayes_pls_golite062009
ubiquitin-protein ligase activity	6.75330204125607	bayes_pls_golite062009
acid-amino acid ligase activity	5.83782824833863	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	4.30935997378918	bayes_pls_golite062009
transcription regulator activity	2.21355731489173	bayes_pls_golite062009
nucleic acid binding	2.13970605403492	bayes_pls_golite062009
DNA binding	1.95596447916631	bayes_pls_golite062009
binding	1.75350658654805	bayes_pls_golite062009
ligase activity	1.68348064141866	bayes_pls_golite062009
transcription repressor activity	1.5236035191291	bayes_pls_golite062009
catalytic activity	0.891402822028799	bayes_pls_golite062009
SUMO ligase activity	0.843488104298821	bayes_pls_golite062009
protein binding	0.726328463755484	bayes_pls_golite062009
NEDD8 ligase activity	0.715654744941217	bayes_pls_golite062009
protein kinase activity	0.443948654247666	bayes_pls_golite062009
protein serine/threonine kinase activity	0.182854082413338	bayes_pls_golite062009
transcription corepressor activity	0.122859425935324	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0501858755083694	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0234849623298925	bayes_pls_golite062009
transcription activator activity	0.0138208971172455	bayes_pls_golite062009
transcription factor binding	0.0104967529560147	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: