YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261580, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	509 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261580, gi|....

Description	E-value	Query Range	Subject Range
gi\|30019633, gi\|... - gi\|30019633\|ref\|NP_831264.1\| ATP-dependent DNA helicase recQ [Bacillus cereus ATCC 14579], gi\|298951...	5.0E-68	[1..509]	[1..509]
gi\|49332602, gi\|... - gi\|49481046\|ref\|YP_035701.1\| ATP-dependent DNA helicase RecQ [Bacillus thuringiensis serovar konkuki...	1.0E-67	[1..509]	[1..509]
gi\|51977332, gi\|... - gi\|52143863\|ref\|YP_082965.1\| ATP-dependent DNA helicase Q [Bacillus cereus E33L], gi\|51977332\|gb\|AAU...	1.0E-67	[1..509]	[1..509]
gi\|163848628, gi... - gi\|76260163\|ref\|ZP_00767803.1\| Helicase, C-terminal:DbpA, RNA-binding:DEAD/DEAH box helicase, N-term... gi\|222526563, gi... - gi\|222526563\|ref\|YP_002571034.1\| DEAD/DEAH box helicase domain protein [Chloroflexus sp. Y-400-fl], ... gi\|53794762 - ref\|ZP_00355887.1\| COG0513: Superfamily II DNA and RNA helicases [Chloroflexus aurantiacus]	1.0E-60	[1..356]	[7..367]
gi\|51856474, gi\|... - gi\|51892785\|ref\|YP_075476.1\| ATP-dependent RNA helicase [Symbiobacterium thermophilum IAM 14863], gi...	2.0E-60	[1..426]	[11..440]
gi\|116333167, gi... - gi\|116333167\|ref\|YP_794694.1\| superfamily II DNA/RNA helicase [Lactobacillus brevis ATCC 367], gi\|11...	6.0E-60	[1..417]	[6..427]
gi\|28377407, gi\|... - gi\|28377407\|ref\|NP_784299.1\| ATP-dependent RNA helicase [Lactobacillus plantarum WCFS1], gi\|28270239... gi\|254555590, gi... - gi\|254555590\|ref\|YP_003062007.1\| ATP-dependent RNA helicase [Lactobacillus plantarum JDM1], gi\|25404... gi\|227853887, gi... - gi\|227897850\|ref\|ZP_04015655.1\| ATP-dependent RNA helicase [Lactobacillus plantarum subsp. plantarum...	2.0E-59	[1..431]	[6..442]
gi\|33566623 - gi\|33566623\|emb\|CAE38832.1\| putative ATP-dependent RNA helicase [Bordetella parapertussis] gi\|33598065 - gi\|33598065\|ref\|NP_885708.1\| putative ATP-dependent RNA helicase [Bordetella parapertussis 12822]	3.0E-59	[2..403]	[23..436]
gi\|3986287 - gi\|3986287\|dbj\|BAA34994.1\| DjVLGB [Dugesia japonica]	3.0E-59	[1..372]	[189..580]
gi\|118578871, gi... - gi\|71837833\|ref\|ZP_00677596.1\| DEAD/DEAH box helicase:Helicase, C-terminal [Pelobacter propionicus D...	4.0E-59	[1..357]	[6..373]

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Predicted Domain #1

Region A:
Residues: [1-459]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLEEYLYKW FGYSEFRPGQ KGVITDLLEG KDVIAMLPTG RGKSMCYQFP GLMREGTVLV  60
   61 VSPLLSLMED QVTQLKYVVK DRVIAFNSFR TLNEKREAMK KLSSYKFIFV SPEMLQSELL 120
  121 IRELKKIHIS LFVVDEAHCI SQWGYDFRPD YKKLNVVIEN IGSPTVLALT ATATKGVLQD 180
  181 IADSLNLKGA AEHVYSIDRP NIAMDVQFVE TIEEKKEALL EQVMYLQGPG IVYCSSRAWT 240
  241 ERLTEYLRGK GVTGVAFYHG GMEHEERMLI QQQFMNNQLQ LVICTSAFGM GVNKANTRYI 300
  301 IHFHYPTNIA SYLQEIGRAG RDGEPSIAIL LCSPLDHDLP ISIIEDELPS KSQIQFLFSL 360
  361 LQERMFQTKE LPIEDVEEIC YNAARFNEQY WRFVRYHLEQ VGIIQQRRLL LEGLSDEIMN 420
  421 RLIAEVEIRL RNKYSELENM KSWIQVKGCR REYVLQQFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.221849
Match:	1oywA
Description:	Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	7.79457008386475	bayes_pls_golite062009
translation factor activity, nucleic acid binding	4.98637553020315	bayes_pls_golite062009
translation regulator activity	4.94658029227343	bayes_pls_golite062009
structural constituent of ribosome	4.56509805974548	bayes_pls_golite062009
structural molecule activity	3.58406348799895	bayes_pls_golite062009
RNA cap binding	3.05696024978364	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
pyrophosphatase activity	2.13284212711072	bayes_pls_golite062009
nucleic acid binding	2.11222585187695	bayes_pls_golite062009
DNA binding	1.7904783386531	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
transcription regulator activity	1.68903321260301	bayes_pls_golite062009
RNA binding	1.60613159109369	bayes_pls_golite062009
	1.44426272235796	bayes_pls_golite062009
RNA helicase activity	1.42791449104435	bayes_pls_golite062009
RNA-dependent ATPase activity	1.39335733374328	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.36724390116598	bayes_pls_golite062009
motor activity	1.34882329548339	bayes_pls_golite062009
DNA-dependent ATPase activity	1.2155186842031	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
structure-specific DNA binding	0.782430219754236	bayes_pls_golite062009
DNA helicase activity	0.72881469450553	bayes_pls_golite062009
double-stranded DNA binding	0.6071273686445	bayes_pls_golite062009
transcription repressor activity	0.607045223341107	bayes_pls_golite062009
transcription factor activity	0.603758349693077	bayes_pls_golite062009
ATP-dependent DNA helicase activity	0.5886142102548	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
four-way junction helicase activity	0.26252931460003	bayes_pls_golite062009
microfilament motor activity	0.2184107989371	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
exodeoxyribonuclease V activity	0.185603938981231	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.147579541298736	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.113504049290503	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.111293884322157	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [460-509]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRKEQELMNC CDYCGITKED YKKRRAQQSD FDYNWETELQ KLFGLEKMEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.522879
Match:	1tf2A
Description:	Crystal structure of SecA:ADP in an open conformation from Bacillus Subtilis
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: