YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39983594, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39983594, gi|....

Description	E-value	Query Range	Subject Range
gi\|78504971, gi\|... - gi\|78687322\|ref\|ZP_00852074.1\| A/G-specific adenine glycosylase MutY [Shewanella sp. ANA-3], gi\|7850...	282.0	[0..22]	[279..5]
gi\|113888199, gi... - gi\|114046757\|ref\|YP_737307.1\| A/G-specific DNA-adenine glycosylase [Shewanella sp. MR-7], gi\|1138881...	281.0	[0..22]	[279..5]
gi\|82404408, gi\|... - gi\|82497582\|ref\|ZP_00883114.1\| A/G-specific adenine glycosylase MutY [Shewanella sp. MR-4], gi\|82404...	281.0	[0..22]	[279..5]
gi\|24349580, gi\|... - gi\|24374879\|ref\|NP_718922.1\| A/G-specific adenine glycosylase [Shewanella oneidensis MR-1], gi\|24349... SO3368 - A/G-specific adenine glycosylase	279.0	[0..22]	[279..5]
gi\|75819192, gi\|... - gi\|75819192\|ref\|ZP_00749285.1\| COG1194: A/G-specific DNA glycosylase [Vibrio cholerae V51], gi\|11621...	277.0	[0..10]	[280..6]
gi\|116189574, gi... - gi\|75829107\|ref\|ZP_00758424.1\| COG1194: A/G-specific DNA glycosylase [Vibrio cholerae MO10], gi\|1161...	276.0	[0..10]	[280..6]
gi\|68546031, gi\|... - gi\|68546031\|ref\|ZP_00585580.1\| A/G-specific adenine glycosylase MutY [Shewanella amazonensis SB2B], ...	275.0	[0..3]	[278..191]
gi\|75822032, gi\|... - gi\|75822032\|ref\|ZP_00751746.1\| COG1194: A/G-specific DNA glycosylase [Vibrio cholerae RC385], gi\|116...	275.0	[0..10]	[280..6]
gi\|75825853 - gi\|75825853\|ref\|ZP_00755288.1\| COG1194: A/G-specific DNA glycosylase [Vibrio cholerae O395]	272.0	[0..10]	[280..6]
gi\|227008550, gi... - gi\|227080662\|ref\|YP_002809213.1\| A/G-specific adenine glycosylase [Vibrio cholerae M66-2], gi\|227008... gi\|121728580, gi... - gi\|121728580\|ref\|ZP_01681601.1\| A/G-specific adenine glycosylase [Vibrio cholerae V52], gi\|121629136... gi\|15640479, gi\|... - gi\|9654877\|gb\|AAF93625.1\| A/G-specific adenine glycosylase [Vibrio cholerae O1 biovar El Tor str. N1... gi\|11354352 - pir\|\|D82320 A/G-specific adenine glycosylase VC0452 [imported] - Vibrio cholerae (strain N16961 sero... gi\|125618186 - gi\|125618186\|gb\|EAZ46730.1\| A/G-specific adenine glycosylase [Vibrio cholerae MO10] gi\|153224226, gi... - gi\|153224226\|ref\|ZP_01954309.1\| A/G-specific adenine glycosylase [Vibrio cholerae MAK 757], gi\|12411... gi\|153823186, gi... - gi\|153823186\|ref\|ZP_01975853.1\| A/G-specific adenine glycosylase [Vibrio cholerae B33], gi\|126519312... gi\|153819148, gi... - gi\|153819148\|ref\|ZP_01971815.1\| A/G-specific adenine glycosylase [Vibrio cholerae NCTC 8457], gi\|126...	272.0	[0..24]	[280..4]

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Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNREQELTHL FRREGLTPAV ADLFRRIVYD WYASQRRELP WRETFDPYAI LVSEIMLQQT  60
   61 QVERVREKYP TFLAEFPNLR ALAAAPLERV LAAWQGLGYN RRAVNLKRCA EAVVASLGGE 120
  121 LPADPNELVR LPGIGTYTSR AVAAFAFNTP LPFIETNIRS VYIHHFFADQ SSIHDRDLMP 180
  181 LIEQTLDRDN PREWYYALMD YGSHLKRLHG NPSRRSSHHT RQTPFKGSNR QVRSRILRAV 240
  241 LENPGISRDA LEKAVGASSE IVGKNLEQLA AEGFIVSRGP GYRIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.0
Match:	1rrsA
Description:	MutY adenine glycosylase in complex with DNA containing an abasic site
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.08559331236111	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.73234184319832	bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity	3.12421941323765	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.54759386266723	bayes_pls_golite062009
catalytic activity	2.50389926428623	bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity	1.80199518353554	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.75218522602775	bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity	1.14337995879633	bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity	0.473206156100251	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.29478804124408	bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity	0.253198605718519	bayes_pls_golite062009
nucleic acid binding	0.161081882647114	bayes_pls_golite062009
DNA binding	0.0468401393186841	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: