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View Structure Prediction Details

Protein: gi|207343419
Organism: Saccharomyces cerevisiae AWRI1631
Length: 551 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|207343419.

Description E-value Query
Range
Subject
Range
gi|207343419 - gi|207343419|gb|EDZ70882.1| YKR017Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941561 - gi|151941561|gb|EDN59924.1| conserved protein [Saccharomyces cerevisiae YJM789]
HEL1_YEAST - E3 ubiquitin-protein ligase HEL2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEL1 PE...
gi|190409839 - gi|190409839|gb|EDV13104.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YKR017C - Putative protein of unknown function; contains a RING finger motif
0.0 [1..551] [1..551]
ari-1 - status:Partially_confirmed UniProt:O01965 protein_id:AAB93645.3
0.0 [45..544] [7..487]
gi|3925602 - gi|3925602|emb|CAA10274.1| Ariadne protein (ARI) [Homo sapiens]
0.0 [85..545] [1..456]
gi|166157476 - gi|166157476|ref|NP_001013126.2| ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [...
ARI1_MOUSE - E3 ubiquitin-protein ligase ARIH1 OS=Mus musculus GN=Arih1 PE=1 SV=3
0.0 [83..545] [4..462]
ARI10_ARATH - Probable E3 ubiquitin-protein ligase ARI10 OS=Arabidopsis thaliana GN=ARI10 PE=2 SV=1
0.0 [47..549] [1..495]
FBpp0305074, FBp... - The gene ariadne is referred to in FlyBase by the symbol Dmel\ari-1 (CG5659, FBgn0017418). It is a p...
0.0 [44..541] [1..493]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGTENDQF YSFDESDSSS IELYESHNTS EFTIHGLVFP KLISVTSQDS EFDINEDEDG  60
   61 VDTIYEGMLD APLTKNNKRI LCEGSVPNLS YECLTTKGIF ERMLQRVDHL QPIFAIPSAD 120
  121 ILILLQHYDW NEERLLEVWT EKMDELLVEL GLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TANIKKDNDY NSHFREVEFK NDFTCIICCD KKDTETFALE CGHEYCINCY RHYIKDKLHE  60
   61 GNIITCMDCS LALKNEDIDK VMGHPSSSKL MDSSIKSFVQ KHNRNYKWCP FADCKSIVHL 120
  121 RDTSSLPEYT RLHYSPFVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.045757
Match: 1rmd__
Description: V(D)J recombination activating protein 1 (RAG1), dimerization domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [294-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNSFHRFCFN CGFEVHSPAD CKITTAWVKK ARKESEILNW VLSHTKECPK CSVNIEKNGG  60
   61 CNHMVCSSCK YEFCWICEGP WAPHGKNFFQ CTM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [387-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKNNEDNKSK NPQDANKTLK KYTFYYRLFN EHEVSAKLDW NLGQTLGTKV HALQERIGIS  60
   61 WIDGQFLSES LKVLNEGRTV LKWSFAVAYY SDASHNLTKI FVDNQMLLAN AVESLSELLQ 120
  121 IKTPEVIMKR RPEFYNKAGY VENRTTALME CGRELLCKGI CKAAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.07217714843839 bayes_pls_golite062009
binding 2.19426901055464 bayes_pls_golite062009
protein binding 1.62051249360163 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription regulator activity 0.553991532499653 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
DNA binding 0.227671243150662 bayes_pls_golite062009
hydrolase activity 0.156835837705934 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
peptidase activity 0.121357659741468 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [392-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNKSKNPQDA NKTLKKYTFY YRLFNEHEVS AKLDWNLGQT LGTKVHALQE RIGISWIDGQ  60
   61 FLSESLKVLN EGRTVLKWSF AVAYYSDASH NLTKIFVDNQ MLLANAVESL SELLQIKTPE 120
  121 VIMKRRPEFY NKAGYVENRT TALMECGREL LCKGICKAAE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle