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View Structure Prediction Details

Protein: gi|229498, gi|66935
Organism: Sus scrofa domesticus
Length: 194 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229498, gi|66935.

Description E-value Query
Range
Subject
Range
gi|230801 - gi|230801|pdb|3ADK| Chain , Adenylate Kinase (E.C.2.7.4.3)
177.0 [0..1] [194..2]
KAD1_RAT - Adenylate kinase isoenzyme 1 OS=Rattus norvegicus GN=Ak1 PE=1 SV=3
177.0 [0..1] [194..1]
gi|61365690 - gi|61365690|gb|AAX42747.1| adenylate kinase 1 [synthetic construct]
176.0 [0..1] [194..1]
gi|109112204 - gi|109112204|ref|XP_001094708.1| PREDICTED: adenylate kinase 1 [Macaca mulatta]
176.0 [0..1] [194..1]
gi|60817675, gi|... - gi|61355727|gb|AAX41170.1| adenylate kinase 1 [synthetic construct], gi|60817675|gb|AAX36433.1| aden...
AK1 - adenylate kinase 1
175.0 [0..1] [194..1]
KAD1_BOVIN - Adenylate kinase isoenzyme 1 OS=Bos taurus GN=AK1 PE=1 SV=2
175.0 [0..1] [194..1]

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Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKLKKSKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRAEVSSG SARGKMLSEI  60
   61 MEKGQLVPLE TVLDMLRDAM VAKVDTSKGF LIDGYPREVK QGEEFERKIG QPTLLLYVDA 120
  121 GPETMTKRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD 180
  181 DVFSQVCTHL DTLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 3adkA
Description: REFINED STRUCTURE OF PORCINE CYTOSOLIC ADENYLATE KINASE AT 2.1 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 5.63633783771436 bayes_pls_golite062009
nucleotide kinase activity 4.87013305162694 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 4.71956130169341 bayes_pls_golite062009
adenylate kinase activity 3.67594732794865 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 2.29455092461489 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.39044805677656 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.27520023113176 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
ion transmembrane transporter activity 1.1237520329736 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.03581449013603 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
guanylate kinase activity 0.98934362137863 bayes_pls_golite062009
cation transmembrane transporter activity 0.940135818362306 bayes_pls_golite062009
structural constituent of ribosome 0.738234102557832 bayes_pls_golite062009
motor activity 0.68122766055454 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
purine nucleotide binding 0.569910969126728 bayes_pls_golite062009
purine ribonucleotide binding 0.568840867400671 bayes_pls_golite062009
ribonucleotide binding 0.568779924702229 bayes_pls_golite062009
nucleotide binding 0.564275755355315 bayes_pls_golite062009
CTP synthase activity 0.554689818807922 bayes_pls_golite062009
microtubule motor activity 0.48522137429998 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
formate-tetrahydrofolate ligase activity 0.21533099279384 bayes_pls_golite062009
ATP binding 0.1860481660648 bayes_pls_golite062009
adenyl ribonucleotide binding 0.152859582615242 bayes_pls_golite062009
adenyl nucleotide binding 0.138615225841109 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
structural molecule activity 0.0558641287316701 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle