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View Structure Prediction Details

Protein: gi|42572335
Organism: Arabidopsis thaliana
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|42572335.

Description E-value Query
Range
Subject
Range
gi|5923675 - gi|5923675|gb|AAD56326.1|AC009326_13 putative mRNA capping enzyme, RNA guanylyltransferase [Arabidop...
371.0 [0..1] [632..1]

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Predicted Domain #1
Region A:
Residues: [1-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVATMDLNAS PQPEEDDEPY VRHLEDYSSR DERIESAVEI ARREREERKK RMRYDKPTHN  60
   61 SQPVFRDQYY QNRNTKAYDR YKIPQGWLDC PPSGNEIGFL VPSKVPLNES YNNHVPPGSR 120
  121 YSFKQVIHNQ RIAGRKLGLV IDLTNTTRYY STTDLKKEGI KHVKIACKGR DAVPDNVSVN 180
  181 AFVNEVNQFV LNLKHSKKYI LVHCTHGHNR TGFMIVHYLM RSGPMNVTQA LKIFSDARPP 240
  241 GIYKPDYIDA LYSFYHEIKP ESVICPSTPE WK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 2c46A
Description: CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [273-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSTELDLNGE ALPDDEDDDG GPAGPVQGFQ EESHQVDVKM SNDDVLGDEI PPDQEEGYRQ  60
   61 FFYRMLSLNI GGRGCSQFPG SHPVSLNREN LQLLRQRYYY ATWKADGTRY MMLLTT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.19
Match: 1ckmA
Description: RNA guanylyltransferase (mRNA capping enzyme); RNA guanylyltransferase (mRNA capping enzyme), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [389-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGCYIVDRSF RFRRVQMRFP FRHPTEGISD KVHHFTLLDG EMIIDTLPDK QKQERRYLIY  60
   61 DMVAINGQSV VERPFYERWK MLEKEVIDPR NHEKARSHIY RYDLEPFRVR RKDFWLLSAV 120
  121 EKVLKGFIPS LSHEADGLIF QGWDDPYVPR THEGLLKWKY PEMNSVDFLY EQDESGRGML 180
  181 SLFERGKKKH MDGNSVVFRD DSDPAEYSGK IVECSWDQDE KVWVSMRVRV DKSTPNDINT 240
  241 FRKVMRSIKD NITEEVLLQE IREIIRLPMY ADRIQMDSKA ARRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.154902
Match: 1p16A
Description: mRNA capping enzyme alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mRNA guanylyltransferase activity 8.90512192081791 bayes_pls_golite062009
RNA guanylyltransferase activity 8.46124967325993 bayes_pls_golite062009
guanylyltransferase activity 5.45528434251369 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.08627215479695 bayes_pls_golite062009
ligase activity, forming phosphoric ester bonds 2.90848936326491 bayes_pls_golite062009
DNA ligase activity 2.88630907730339 bayes_pls_golite062009
ligase activity 2.7348192562888 bayes_pls_golite062009
RNA binding 2.41160981373213 bayes_pls_golite062009
hydrolase activity 2.27001407788735 bayes_pls_golite062009
catalytic activity 2.15370807854636 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
structural constituent of ribosome 1.6315894906264 bayes_pls_golite062009
binding 1.63149986094272 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
1.5765009871268 bayes_pls_golite062009
nucleic acid binding 1.39097817404242 bayes_pls_golite062009
DNA binding 1.33524321669723 bayes_pls_golite062009
structural molecule activity 1.32534541097134 bayes_pls_golite062009
ribonuclease activity 1.19236946227657 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.15212468568198 bayes_pls_golite062009
exoribonuclease activity 1.10445667068538 bayes_pls_golite062009
DNA ligase (ATP) activity 1.02324195596817 bayes_pls_golite062009
transcription regulator activity 0.996884322431837 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.83268201349295 bayes_pls_golite062009
translation regulator activity 0.613904794456162 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
DNA ligase (NAD+) activity 0.571203360462711 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.566068090112017 bayes_pls_golite062009
RNA polymerase activity 0.477127926059749 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.477127926059749 bayes_pls_golite062009
mRNA binding 0.4162128308402 bayes_pls_golite062009
sequence-specific DNA binding 0.32084431704638 bayes_pls_golite062009
translation initiation factor activity 0.30211828233765 bayes_pls_golite062009
transcription factor activity 0.298729064067577 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.287720615514972 bayes_pls_golite062009
protein binding 0.229784545879049 bayes_pls_golite062009
ATP binding 0.17947590671995 bayes_pls_golite062009
adenyl ribonucleotide binding 0.148991737494582 bayes_pls_golite062009
adenyl nucleotide binding 0.138964074823321 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle