From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.861650286316] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
ASI1 |
|
|
|
ASI3 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear inner membrane | 2.779E-6 | 2 | 11 | 2 | 6292 |
nuclear membrane | 2.3525E-4 | 2 | 97 | 2 | 6292 |
endoplasmic reticulum membrane | 4.4352E-4 | 2 | 133 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
organelle inner membrane | 8.5997E-4 | 2 | 185 | 2 | 6292 |
nuclear envelope | 9.9543E-4 | 2 | 199 | 2 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.3539E-3 | 2 | 232 | 2 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ubiquitin-dependent protein catabolic process | 6.1087E-4 | 2 | 156 | 2 | 6292 |
modification-dependent protein catabolic process | 6.1087E-4 | 2 | 156 | 2 | 6292 |
proteolysis involved in cellular protein catabolic process | 6.3467E-4 | 2 | 159 | 2 | 6292 |
modification-dependent macromolecule catabolic process | 6.7534E-4 | 2 | 164 | 2 | 6292 |
cellular protein catabolic process | 7.3441E-4 | 2 | 171 | 2 | 6292 |
proteolysis | 8.8816E-4 | 2 | 188 | 2 | 6292 |
protein catabolic process | 8.9766E-4 | 2 | 189 | 2 | 6292 |
cellular macromolecule catabolic process | 1.7674E-3 | 2 | 265 | 2 | 6292 |
macromolecule catabolic process | 2.1762E-3 | 2 | 294 | 2 | 6292 |
cellular catabolic process | 4.3405E-3 | 2 | 415 | 2 | 6292 |
catabolic process | 6.2027E-3 | 2 | 496 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ubiquitin-protein ligase activity | 8.0641E-5 | 2 | 57 | 2 | 6292 |
small conjugating protein ligase activity | 9.5546E-5 | 2 | 62 | 2 | 6292 |
acid-amino acid ligase activity | 1.2556E-4 | 2 | 71 | 2 | 6292 |
ligase activity, forming carbon-nitrogen bonds | 2.2085E-4 | 2 | 94 | 2 | 6292 |
ligase activity | 5.6464E-4 | 2 | 150 | 2 | 6292 |