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A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. Located in the nuclear inner membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane. The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. The lipid bilayer surrounding an organelle. The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane. The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).

View Gene Ontology (GO) Term


Name: nuclear inner membrane
Acc: GO:0005637
Aspect: Cellular Component
Desc: The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
  • inner envelope
Proteins in PDR annotated with:
   This term: 49 [Search]
   Term or descendants: 91 [Search]


GO:0005637 - nuclear inner membrane (interactive image map)

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