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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.886307382608]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ASI3
  • endoplasmic reticulum membrane
  • nuclear inner membrane
    		•
  • ubiquitin-dependent protein catabolic process
    		•
  • ubiquitin-protein ligase activity
    		•
    SSM4
  • nuclear envelope
  • nuclear inner membrane
  • integral to endoplasmic reticulum membrane
    		•
  • ER-associated protein catabolic process
    		•
  • ubiquitin-protein ligase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear inner membrane 2.779E-6 2 11 2 6292
    nuclear membrane 2.3525E-4 2 97 2 6292
    endoplasmic reticulum membrane 4.4352E-4 2 133 2 6292
    endoplasmic reticulum part 5.6464E-4 2 150 2 6292
    subsynaptic reticulum 5.6464E-4 2 150 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    nuclear envelope 9.9543E-4 2 199 2 6292
    nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
    endoplasmic reticulum 3.3381E-3 2 364 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292
    integral to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292
    intrinsic to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
    modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
    cellular protein catabolic process 7.3441E-4 2 171 2 6292
    proteolysis 8.8816E-4 2 188 2 6292
    protein catabolic process 8.9766E-4 2 189 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ubiquitin-protein ligase activity 8.0641E-5 2 57 2 6292
    small conjugating protein ligase activity 9.5546E-5 2 62 2 6292
    acid-amino acid ligase activity 1.2556E-4 2 71 2 6292
    ligase activity, forming carbon-nitrogen bonds 2.2085E-4 2 94 2 6292
    ligase activity 5.6464E-4 2 150 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle