From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.11643321733] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
SCF ubiquitin ligase complex | 2.779E-6 | 2 | 11 | 2 | 6292 |
cullin-RING ubiquitin ligase complex | 4.5979E-6 | 2 | 14 | 2 | 6292 |
ubiquitin ligase complex | 4.5626E-5 | 2 | 43 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
modification-dependent protein catabolic process | 6.1087E-4 | 2 | 156 | 2 | 6292 |
ubiquitin-dependent protein catabolic process | 6.1087E-4 | 2 | 156 | 2 | 6292 |
proteolysis involved in cellular protein catabolic process | 6.3467E-4 | 2 | 159 | 2 | 6292 |
modification-dependent macromolecule catabolic process | 6.7534E-4 | 2 | 164 | 2 | 6292 |
cellular protein catabolic process | 7.3441E-4 | 2 | 171 | 2 | 6292 |
proteolysis | 8.8816E-4 | 2 | 188 | 2 | 6292 |
protein catabolic process | 8.9766E-4 | 2 | 189 | 2 | 6292 |
cellular macromolecule catabolic process | 1.7674E-3 | 2 | 265 | 2 | 6292 |
macromolecule catabolic process | 2.1762E-3 | 2 | 294 | 2 | 6292 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.224E-3 | 2 | 7 | 1 | 6292 |
protein ubiquitination during ubiquitin-dependent protein catabolic process | 3.4937E-3 | 2 | 11 | 1 | 6292 |
cellular catabolic process | 4.3405E-3 | 2 | 415 | 2 | 6292 |
catabolic process | 6.2027E-3 | 2 | 496 | 2 | 6292 |
G2/M transition of mitotic cell cycle | 9.1975E-3 | 2 | 29 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ubiquitin-protein ligase activity | 8.0641E-5 | 2 | 57 | 2 | 6292 |
small conjugating protein ligase activity | 9.5546E-5 | 2 | 62 | 2 | 6292 |
acid-amino acid ligase activity | 1.2556E-4 | 2 | 71 | 2 | 6292 |
ligase activity, forming carbon-nitrogen bonds | 2.2085E-4 | 2 | 94 | 2 | 6292 |
ligase activity | 5.6464E-4 | 2 | 150 | 2 | 6292 |
DNA replication origin binding | 4.1283E-3 | 2 | 13 | 1 | 6292 |
protein binding, bridging | 6.3477E-3 | 2 | 20 | 1 | 6292 |
protein binding | 9.4468E-3 | 2 | 612 | 2 | 6292 |