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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.13223829578]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
INP52
  • membrane fraction
  • actin cortical patch
    		•
  • cellular cell wall organization
  • inositol lipid-mediated signaling
  • endocytosis
  • phosphoinositide dephosphorylation
    		•
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
  • inositol-polyphosphate 5-phosphatase activity
    		•
    INP53
  • membrane fraction
  • actin cortical patch
    		•
  • cellular cell wall organization
  • inositol lipid-mediated signaling
  • endocytosis
  • phosphoinositide dephosphorylation
    		•
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
  • inositol-polyphosphate 5-phosphatase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    actin cortical patch 4.1432E-5 2 41 2 6292
    cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
    cortical cytoskeleton 6.6999E-5 2 52 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    membrane fraction 2.0691E-4 2 91 2 6292
    insoluble fraction 2.0691E-4 2 91 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cell fraction 4.1715E-4 2 129 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    phospholipid dephosphorylation 1.0611E-6 2 7 2 6292
    phosphoinositide dephosphorylation 1.0611E-6 2 7 2 6292
    inositol lipid-mediated signaling 6.0632E-6 2 16 2 6292
    phosphoinositide-mediated signaling 6.0632E-6 2 16 2 6292
    lipid modification 1.3945E-5 2 24 2 6292
    second-messenger-mediated signaling 2.1979E-5 2 30 2 6292
    dephosphorylation 3.9411E-5 2 40 2 6292
    phosphoinositide metabolic process 4.7798E-5 2 44 2 6292
    glycerophospholipid metabolic process 1.051E-4 2 65 2 6292
    glycerolipid metabolic process 1.2202E-4 2 70 2 6292
    endocytosis 1.9342E-4 2 88 2 6292
    membrane invagination 2.2085E-4 2 94 2 6292
    phospholipid metabolic process 2.304E-4 2 96 2 6292
    organophosphate metabolic process 2.3525E-4 2 97 2 6292
    intracellular signal transduction 3.312E-4 2 115 2 6292
    intracellular signaling pathway 5.2022E-4 2 144 2 6292
    external encapsulating structure organization 7.5174E-4 2 173 2 6292
    cell wall organization 7.5174E-4 2 173 2 6292
    cellular cell wall organization 7.5174E-4 2 173 2 6292
    cellular lipid metabolic process 8.5067E-4 2 184 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    membrane organization 9.8542E-4 2 198 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    cellular cell wall organization or biogenesis 1.0877E-3 2 208 2 6292
    cell wall organization or biogenesis 1.0877E-3 2 208 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    phosphorus metabolic process 1.3191E-3 2 229 2 6292
    phosphate metabolic process 1.3191E-3 2 229 2 6292
    lipid metabolic process 1.4491E-3 2 240 2 6292
    signaling 1.598E-3 2 252 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    inositol-polyphosphate 5-phosphatase activity 1.5158E-7 2 3 2 6292
    inositol trisphosphate phosphatase activity 1.5158E-7 2 3 2 6292
    phosphoinositide 5-phosphatase activity 3.0316E-7 2 4 2 6292
    phosphatidylinositol bisphosphate phosphatase activity 3.0316E-7 2 4 2 6292
    phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 3.0316E-7 2 4 2 6292
    inositol or phosphatidylinositol phosphatase activity 1.819E-6 2 9 2 6292
    phosphatase activity 1.8902E-4 2 87 2 6292
    phosphoric ester hydrolase activity 2.6026E-4 2 102 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    YRC Informatics Platform - Version 3.0
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