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Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. Catalysis of the removal of one of the three phosphate groups of an inositol trisphosphate. Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: inositol-polyphosphate 5-phosphatase activity
Acc: GO:0004445
Aspect: Molecular Function
Desc: Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
Synonyms:
  • inositol polyphosphate-5-phosphatase activity
  • Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity
  • InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity
  • myo-inositol-1,4,5-trisphosphate 5-phosphatase activity
  • Ins(1,4,5)P(3) 5-phosphatase activity
  • D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity
  • inosine triphosphatase activity
  • 5PTase activity
  • inositol trisphosphate phosphomonoesterase activity
  • inositol triphosphate 5-phosphomonoesterase activity
  • D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity
  • inositol phosphate 5-phosphomonoesterase activity
  • InsP3/Ins(1,3,4,5)P4 5-phosphatase activity
  • type I inositol-polyphosphate phosphatase activity
  • inositol-1,4,5-trisphosphate 5-phosphatase activity
  • Ins(1,4,5)P3 5-phosphatase activity
  • type II inositol polyphosphate 5-phosphatase activity
  • inositol 1,4,5-trisphosphate phosphatase activity
  • 1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity
  • L-myo-inositol 1,4,5-trisphosphate-monoesterase activity
  • inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity
  • type II inositol-1,4,5-trisphosphate 5-phosphatase activity
  • D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 30 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004445 - inositol-polyphosphate 5-phosphatase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle