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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.27330628969]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

anaphase-promoting complex 8.6401E-6 2 19 2 6292
nuclear ubiquitin ligase complex 1.2783E-5 2 23 2 6292
ubiquitin ligase complex 4.5626E-5 2 43 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cyclin catabolic process 3.9411E-6 2 13 2 6292
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 6.0632E-6 2 16 2 6292
mitotic spindle elongation 1.0611E-5 2 21 2 6292
spindle elongation 1.0611E-5 2 21 2 6292
mitotic metaphase/anaphase transition 3.3651E-5 2 37 2 6292
mitotic spindle organization 5.6994E-5 2 48 2 6292
spindle organization 5.9419E-5 2 49 2 6292
protein ubiquitination 1.051E-4 2 65 2 6292
mitotic sister chromatid segregation 1.0838E-4 2 66 2 6292
sister chromatid segregation 1.1854E-4 2 69 2 6292
proteasomal protein catabolic process 1.1854E-4 2 69 2 6292
proteasomal ubiquitin-dependent protein catabolic process 1.1854E-4 2 69 2 6292
protein modification by small protein conjugation 1.8468E-4 2 86 2 6292
microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
mitosis 2.7062E-4 2 104 2 6292
nuclear division 2.8118E-4 2 106 2 6292
microtubule-based process 3.0847E-4 2 111 2 6292
organelle fission 3.1973E-4 2 113 2 6292
protein modification by small protein conjugation or removal 3.2544E-4 2 114 2 6292
chromosome segregation 4.1068E-4 2 128 2 6292
M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
cellular protein catabolic process 7.3441E-4 2 171 2 6292
proteolysis 8.8816E-4 2 188 2 6292
protein catabolic process 8.9766E-4 2 189 2 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
macromolecule catabolic process 2.1762E-3 2 294 2 6292
M phase 2.1762E-3 2 294 2 6292
post-translational protein modification 3.2108E-3 2 357 2 6292
cell cycle phase 3.5621E-3 2 376 2 6292
cellular catabolic process 4.3405E-3 2 415 2 6292
cell cycle process 6.0534E-3 2 490 2 6292
catabolic process 6.2027E-3 2 496 2 6292
protein modification process 6.278E-3 2 499 2 6292
cell cycle 6.95E-3 2 525 2 6292
chromosome organization 7.7677E-3 2 555 2 6292
macromolecule modification 8.1649E-3 2 569 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ubiquitin-protein ligase activity 8.0641E-5 2 57 2 6292
small conjugating protein ligase activity 9.5546E-5 2 62 2 6292
acid-amino acid ligase activity 1.2556E-4 2 71 2 6292
ligase activity, forming carbon-nitrogen bonds 2.2085E-4 2 94 2 6292
ligase activity 5.6464E-4 2 150 2 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle