From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.30298514007] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
delta DNA polymerase complex | 1.5158E-7 | 2 | 3 | 2 | 6292 |
DNA polymerase complex | 2.2737E-6 | 2 | 10 | 2 | 6292 |
nuclear replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
nuclear replication fork | 9.6001E-6 | 2 | 20 | 2 | 6292 |
replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mutagenesis | 1.819E-6 | 2 | 9 | 2 | 6292 |
base-excision repair | 3.3348E-6 | 2 | 12 | 2 | 6292 |
leading strand elongation | 5.3053E-6 | 2 | 15 | 2 | 6292 |
postreplication repair | 7.7306E-6 | 2 | 18 | 2 | 6292 |
lagging strand elongation | 7.7306E-6 | 2 | 18 | 2 | 6292 |
mismatch repair | 1.7735E-5 | 2 | 27 | 2 | 6292 |
DNA strand elongation | 2.3495E-5 | 2 | 31 | 2 | 6292 |
DNA strand elongation involved in DNA replication | 2.3495E-5 | 2 | 31 | 2 | 6292 |
nucleotide-excision repair | 3.552E-5 | 2 | 38 | 2 | 6292 |
obsolete_biological_process | 8.9432E-5 | 2 | 60 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
maintenance of fidelity involved in DNA-dependent DNA replication | 3.1786E-4 | 2 | 1 | 1 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
DNA repair | 9.2646E-4 | 2 | 192 | 2 | 6292 |
response to DNA damage stimulus | 1.4011E-3 | 2 | 236 | 2 | 6292 |
cellular response to stress | 2.1173E-3 | 2 | 290 | 2 | 6292 |
cellular response to stimulus | 3.6193E-3 | 2 | 379 | 2 | 6292 |
response to stress | 6.2277E-3 | 2 | 497 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
single-stranded DNA specific exodeoxyribonuclease activity | 1.5158E-7 | 2 | 3 | 2 | 6292 |
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity | 1.5158E-7 | 2 | 3 | 2 | 6292 |
3'-5'-exodeoxyribonuclease activity | 7.579E-7 | 2 | 6 | 2 | 6292 |
exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 1.4147E-6 | 2 | 8 | 2 | 6292 |
exodeoxyribonuclease activity | 1.819E-6 | 2 | 9 | 2 | 6292 |
deoxyribonuclease activity | 2.0514E-5 | 2 | 29 | 2 | 6292 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 2.8346E-5 | 2 | 34 | 2 | 6292 |
3'-5' exonuclease activity | 3.0063E-5 | 2 | 35 | 2 | 6292 |
exonuclease activity | 5.2295E-5 | 2 | 46 | 2 | 6292 |
nuclease activity | 9.9543E-4 | 2 | 199 | 2 | 6292 |
hydrolase activity, acting on ester bonds | 2.929E-3 | 2 | 341 | 2 | 6292 |