YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cop1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADR1
  • nucleus
  • regulation of carbohydrate metabolic process
  • transcription
  • peroxisome organization
  • negative regulation of transcription from RNA polymerase II promoter by glucose
  • transcription factor activity
  • ATP3
  • mitochondrial proton-transporting ATP synthase, central stalk
  • mitochondrion
  • ATP synthesis coupled proton transport
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
  • COP1
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • PHO86
  • endoplasmic reticulum
  • phosphate transport
  • secretory pathway
  • protein folding
  • molecular_function
  • PRB1
  • fungal-type vacuole lumen
  • fungal-type vacuole
  • cellular response to starvation
  • sporulation resulting in formation of a cellular spore
  • vacuolar protein catabolic process
  • serine-type endopeptidase activity
  • RET2
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • protein binding
  • SEC21
  • endosome
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • SEC26
  • coated vesicle
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • molecular_function
  • SEC27
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • SEC28
  • endosome
  • COPI vesicle coat
  • vesicle coating
  • ER to Golgi vesicle-mediated transport
  • molecular_function
  • TRP3
  • cytoplasm
  • anthranilate synthase complex
  • tryptophan biosynthetic process
  • indole-3-glycerol-phosphate synthase activity
  • anthranilate synthase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    COPI coated vesicle membrane 4.5047E-16 11 9 6 6292
    COPI vesicle coat 4.5047E-16 11 9 6 6292
    Golgi-associated vesicle membrane 4.274E-14 11 16 6 6292
    COPI-coated vesicle 2.8863E-13 11 21 6 6292
    vesicle coat 7.0903E-12 11 34 6 6292
    coated vesicle membrane 8.5513E-12 11 35 6 6292
    cytoplasmic vesicle membrane 8.5513E-12 11 35 6 6292
    vesicle membrane 8.5513E-12 11 35 6 6292
    membrane coat 1.4514E-11 11 38 6 6292
    coated membrane 1.4514E-11 11 38 6 6292
    cytoplasmic vesicle part 1.7142E-11 11 39 6 6292
    Golgi-associated vesicle 2.0153E-11 11 40 6 6292
    Golgi membrane 7.2968E-11 11 49 6 6292
    coated vesicle 1.9241E-9 11 83 6 6292
    membrane-bounded vesicle 9.0613E-9 11 107 6 6292
    cytoplasmic vesicle 9.0613E-9 11 107 6 6292
    cytoplasmic membrane-bounded vesicle 9.0613E-9 11 107 6 6292
    vesicle 1.0717E-8 11 110 6 6292
    Golgi apparatus part 1.7255E-8 11 119 6 6292
    Golgi apparatus 1.5242E-7 11 171 6 6292
    endomembrane system 2.1716E-5 11 398 6 6292
    membrane part 3.1254E-5 11 662 7 6292
    organelle membrane 4.1907E-5 11 692 7 6292
    protein complex 1.0923E-4 11 1137 8 6292
    cytoplasmic part 6.3747E-4 11 2482 10 6292
    membrane 1.4344E-3 11 1198 7 6292
    macromolecular complex 1.5504E-3 11 1635 8 6292
    anthranilate synthase complex 3.4937E-3 11 2 1 6292
    mitochondrial proton-transporting ATP synthase, central stalk 5.2364E-3 11 3 1 6292
    proton-transporting ATP synthase, central stalk 5.2364E-3 11 3 1 6292
    proton-transporting ATP synthase complex, catalytic core F(1) 8.7135E-3 11 5 1 6292
    mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) 8.7135E-3 11 5 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ER to Golgi vesicle-mediated transport 1.9241E-9 11 83 6 6292
    retrograde vesicle-mediated transport, Golgi to ER 7.4149E-8 11 26 4 6292
    Golgi vesicle transport 1.3713E-7 11 168 6 6292
    vesicle-mediated transport 8.7401E-6 11 340 6 6292
    transport 4.0785E-5 11 997 8 6292
    establishment of localization 4.43E-5 11 1008 8 6292
    localization 6.4656E-5 11 1060 8 6292
    intracellular transport 1.4116E-4 11 553 6 6292
    establishment of localization in cell 2.2088E-4 11 599 6 6292
    cellular localization 3.2773E-4 11 643 6 6292
    cellular response to external stimulus 1.6022E-3 11 35 2 6292
    cellular response to extracellular stimulus 1.6022E-3 11 35 2 6292
    cellular response to nutrient levels 1.6022E-3 11 35 2 6292
    response to extracellular stimulus 1.8876E-3 11 38 2 6292
    response to nutrient levels 1.8876E-3 11 38 2 6292
    response to external stimulus 1.8876E-3 11 38 2 6292
    cell communication 3.1247E-3 11 49 2 6292
    vesicle coating 6.9763E-3 11 4 1 6292
    membrane budding 8.7135E-3 11 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    indole-3-glycerol-phosphate synthase activity 1.7483E-3 11 1 1 6292
    anthranilate synthase activity 3.4937E-3 11 2 1 6292
    oxo-acid-lyase activity 6.9763E-3 11 4 1 6292
    serine-type endopeptidase activity 6.9763E-3 11 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle