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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rpc19. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA polymerase complex 5.9744E-14 7 31 6 6292
nuclear DNA-directed RNA polymerase complex 5.9744E-14 7 31 6 6292
DNA-directed RNA polymerase complex 5.9744E-14 7 31 6 6292
DNA-directed RNA polymerase I complex 5.1118E-13 7 14 5 6292
nucleolar part 3.094E-10 7 45 5 6292
DNA-directed RNA polymerase III complex 5.6973E-7 7 17 3 6292
nucleolus 8.0465E-7 7 211 5 6292
nuclear lumen 8.8765E-7 7 453 6 6292
organelle lumen 8.3215E-6 7 660 6 6292
intracellular organelle lumen 8.3215E-6 7 660 6 6292
membrane-enclosed lumen 1.1789E-5 7 700 6 6292
nuclear part 1.7083E-4 7 1103 6 6292
protein complex 2.0393E-4 7 1137 6 6292
non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
intracellular non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
macromolecular complex 1.6651E-3 7 1635 6 6292
nucleoplasm part 1.817E-3 7 245 3 6292
nucleoplasm 2.2543E-3 7 264 3 6292
nucleus 5.8629E-3 7 2041 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription from RNA polymerase I promoter 3.6232E-11 7 30 5 6292
transcription, DNA-dependent 1.657E-6 7 503 6 6292
RNA biosynthetic process 1.7576E-6 7 508 6 6292
transcription 2.8813E-6 7 552 6 6292
transcription from RNA polymerase III promoter 6.9973E-6 7 38 3 6292
RNA metabolic process 7.3069E-5 7 954 6 6292
cellular macromolecule biosynthetic process 2.6203E-4 7 1187 6 6292
macromolecule biosynthetic process 2.6461E-4 7 1189 6 6292
ribosome biogenesis 2.7556E-4 7 346 4 6292
ribonucleoprotein complex biogenesis 3.725E-4 7 374 4 6292
gene expression 4.1171E-4 7 1283 6 6292
nucleic acid metabolic process 7.2556E-4 7 1415 6 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.3005E-3 7 1566 6 6292
cellular biosynthetic process 1.3053E-3 7 1567 6 6292
biosynthetic process 1.4816E-3 7 1602 6 6292
cellular nitrogen compound metabolic process 2.6186E-3 7 1770 6 6292
nitrogen compound metabolic process 2.8003E-3 7 1791 6 6292
cellular component biogenesis 3.9065E-3 7 694 4 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA polymerase activity 1.0908E-13 7 34 6 6292
DNA-directed RNA polymerase activity 1.0908E-13 7 34 6 6292
nucleotidyltransferase activity 2.2717E-9 7 168 6 6292
transferase activity, transferring phosphorus-containing groups 5.6504E-7 7 420 6 6292
transferase activity 2.5374E-5 7 797 6 6292
catalytic activity 7.8491E-3 7 2150 6 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle