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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ume1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 3.8264E-5 3 23 2 6292
chromatin remodeling complex 7.2776E-4 3 99 2 6292
Sin3 complex 1.9063E-3 3 4 1 6292
Sin3-type complex 2.3825E-3 3 5 1 6292
nucleoplasm part 4.414E-3 3 245 2 6292
nucleoplasm 5.1161E-3 3 264 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylation 7.0488E-8 3 27 3 6292
protein amino acid deacetylation 8.8056E-8 3 29 3 6292
covalent chromatin modification 2.6445E-6 3 88 3 6292
histone modification 2.6445E-6 3 88 3 6292
chromatin modification 1.8706E-5 3 168 3 6292
chromatin silencing at rDNA 2.3152E-5 3 18 2 6292
chromatin organization 3.3104E-5 3 203 3 6292
double-strand break repair via nonhomologous end joining 4.5363E-5 3 25 2 6292
chromatin silencing at silent mating-type cassette 7.9771E-5 3 33 2 6292
non-recombinational repair 8.4748E-5 3 34 2 6292
post-translational protein modification 1.8121E-4 3 357 3 6292
chromatin silencing at telomere 2.2383E-4 3 55 2 6292
double-strand break repair 2.4051E-4 3 57 2 6292
negative regulation of transcription from RNA polymerase II promoter 2.6665E-4 3 60 2 6292
protein modification process 4.9605E-4 3 499 3 6292
positive regulation of transcription from RNA polymerase II promoter 5.2382E-4 3 84 2 6292
chromosome organization 6.8292E-4 3 555 3 6292
macromolecule modification 7.3601E-4 3 569 3 6292
negative regulation of gene expression, epigenetic 7.4253E-4 3 100 2 6292
gene silencing 7.4253E-4 3 100 2 6292
regulation of gene expression, epigenetic 7.4253E-4 3 100 2 6292
chromatin silencing 7.4253E-4 3 100 2 6292
positive regulation of transcription, DNA-dependent 7.8773E-4 3 103 2 6292
positive regulation of RNA metabolic process 8.5005E-4 3 107 2 6292
positive regulation of transcription 9.3124E-4 3 112 2 6292
positive regulation of gene expression 9.3124E-4 3 112 2 6292
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0335E-3 3 118 2 6292
positive regulation of nitrogen compound metabolic process 1.0335E-3 3 118 2 6292
positive regulation of macromolecule biosynthetic process 1.0335E-3 3 118 2 6292
positive regulation of biosynthetic process 1.0866E-3 3 121 2 6292
positive regulation of cellular biosynthetic process 1.0866E-3 3 121 2 6292
positive regulation of macromolecule metabolic process 1.178E-3 3 126 2 6292
positive regulation of metabolic process 1.2346E-3 3 129 2 6292
positive regulation of cellular metabolic process 1.2346E-3 3 129 2 6292
positive regulation of cellular process 1.3717E-3 3 136 2 6292
positive regulation of biological process 1.3919E-3 3 137 2 6292
negative regulation of transcription, DNA-dependent 1.8258E-3 3 157 2 6292
negative regulation of RNA metabolic process 1.849E-3 3 158 2 6292
negative regulation of transcription 1.9912E-3 3 164 2 6292
negative regulation of gene expression 1.9912E-3 3 164 2 6292
regulation of cellular process 2.0181E-3 3 796 3 6292
regulation of biological process 2.2389E-3 3 824 3 6292
negative regulation of macromolecule biosynthetic process 2.2655E-3 3 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3959E-3 3 180 2 6292
negative regulation of nitrogen compound metabolic process 2.3959E-3 3 180 2 6292
negative regulation of biosynthetic process 2.6396E-3 3 189 2 6292
negative regulation of cellular biosynthetic process 2.6396E-3 3 189 2 6292
DNA repair 2.7234E-3 3 192 2 6292
negative regulation of macromolecule metabolic process 2.7234E-3 3 192 2 6292
negative regulation of cellular metabolic process 3.2225E-3 3 209 2 6292
negative regulation of metabolic process 3.2531E-3 3 210 2 6292
regulation of transcription from RNA polymerase II promoter 3.8286E-3 3 228 2 6292
response to DNA damage stimulus 4.0991E-3 3 236 2 6292
loss of chromatin silencing involved in replicative cell aging 4.2857E-3 3 9 1 6292
negative regulation of cellular process 4.5939E-3 3 250 2 6292
negative regulation of biological process 4.7035E-3 3 253 2 6292
progressive alteration of chromatin involved in replicative cell aging 4.7611E-3 3 10 1 6292
loss of chromatin silencing 4.7611E-3 3 10 1 6292
cellular protein metabolic process 4.9618E-3 3 1074 3 6292
progressive alteration of chromatin involved in cell aging 5.2364E-3 3 11 1 6292
positive regulation of gene expression, epigenetic 5.2364E-3 3 11 1 6292
regulation of gene silencing 5.2364E-3 3 11 1 6292
negative regulation of gene silencing 5.2364E-3 3 11 1 6292
regulation of chromatin silencing 5.2364E-3 3 11 1 6292
negative regulation of chromatin silencing 5.2364E-3 3 11 1 6292
organelle organization 5.734E-3 3 1127 3 6292
protein metabolic process 5.8726E-3 3 1136 3 6292
cellular response to stress 6.1581E-3 3 290 2 6292
biological regulation 7.1507E-3 3 1213 3 6292
transcription from RNA polymerase II promoter 8.1809E-3 3 335 2 6292
regulation of transcription, DNA-dependent 9.321E-3 3 358 2 6292
regulation of RNA metabolic process 9.5782E-3 3 363 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription corepressor activity 1.3495E-8 3 16 3 6292
histone deacetylase activity 1.1953E-7 3 32 3 6292
protein deacetylase activity 1.1953E-7 3 32 3 6292
deacetylase activity 1.5773E-7 3 35 3 6292
transcription cofactor activity 2.3809E-7 3 40 3 6292
transcription factor binding 2.974E-7 3 43 3 6292
transcription repressor activity 3.1916E-7 3 44 3 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4.1681E-7 3 48 3 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.9799E-6 3 80 3 6292
transcription coactivator activity 3.1768E-5 3 21 2 6292
transcription regulator activity 1.5509E-4 3 339 3 6292
transcription activator activity 2.7566E-4 3 61 2 6292
protein binding 9.1614E-4 3 612 3 6292
hydrolase activity 3.0267E-3 3 911 3 6292
binding 8.6823E-3 3 1294 3 6292

YRC Informatics Platform - Version 3.0
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